Results 61 to 70 of about 120,030,237 (240)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Medical assistance in dying: The Canadian experience

open access: yes, 2017
Canada is in the midst of implementing new and rapidly evolving policies on medical assistance in dying (MAID). Following the landmark Canadian Supreme Court Carter v.
K. Gaind
core   +1 more source

Discrimination and Socially Embedded Suffering: Extending Grant’s Critique of Track 2 MAID to Mental Illness

open access: yesCanadian Journal of Bioethics
In her paper entitled “Why Track 2 MAiD is Discriminatory,” Isabel Grant offers a compelling disability justice-based critique of Canada’s evolving MAID regime. She argues that Track 2 MAID, which concerns persons who are not approaching the end of life,
Nicholas Dunn
doaj   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng   +3 more
wiley   +1 more source

Medical assistance in dying (Chancellor's Lecture Series)

open access: yes, 2016
In February 2015, the Supreme Court of Canada ruled that the prohibition against physician-assisted dying violated the constitutional right to 'life, liberty, and security of the person'.
Harvey Max Chochinov   +1 more
core   +1 more source

Supplemental Material, sj-doc-1-nej-10.1177_09697330211012049 - Medical assistance in dying legislation: Hospice palliative care providers’ perspectives

open access: yes, 2021
Supplemental Material, sj-doc-1-nej-10.1177_09697330211012049 for Medical assistance in dying legislation: Hospice palliative care providers’ perspectives by Soodabeh Joolaee, Anita Ho, Kristie Serota, Matthieu Hubert and Daniel Z Buchman in Nursing ...
Matthieu Hubert (11468643)   +4 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Ethical arguments against coercing provider participation in MAiD (medical assistance in dying) in Ontario, Canada

open access: yesBMC Medical Ethics, 2020
It has historically been a crime in Canada to provide assistance to someone in ending their own life, however, this paradigm was inverted in 2015 when the Supreme Court of Canada (SCC) ruled that restrictions on this practice, within certain defined ...
Travis Carpenter, Lucas Vivas
doaj   +1 more source

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