Results 71 to 80 of about 225,694 (302)
Assisted Dying in Canada: Ideology Masquerading as Medicine?
Canadian Journal of BioethicsThe Canadian medical assistance in dying (MAID) law is commonly understood as a type of medically-based euthanasia and/or assisted suicide (EAS) law. I argue it is instead an autonomy-only EAS regime masquerading as such.
Scott Y. H. Kim
doaj +1 more source
L’assistance à mourir : un tour d’horizon comparatif des définitions juridiques
Sociologies, 2023 Euthanasia, assisted suicide, medical assistance in dying, death with dignity: these and many other different terms are used around the world to capture various types of assistance in dying.
Jocelyn Downie +3 more
doaj
Dying to go to court: demanding a legal remedy to end-of-life uncertainty [PDF]
, 2015 No abstract ...
Richards, N.
core
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Does Allowing Track 2 MAiD Harm Disabled People?
Canadian Journal of BioethicsIn 2021, in response to the Superior Court of Quebec’s decision in Truchon v. Canada, the Canadian Parliament amended the Criminal Code to allow Medical Assistance in Dying (MAiD) for some people who don’t have a “reasonably foreseeable natural death ...
Nicholas Abernethy
doaj +1 more source
The Constitutional Right to Die: Ethical Considerations [PDF]
, 1997 In this commentary, the author first looks at some ethical reasoning supporting physician-assisted dying. Second, he examines some of the lines that have been drawn between withdrawing and withholding life-sustaining treatment on the one hand, and ...
Gostin, Lawrence O.
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Drawing a Line Between Killing and Letting Die: The Law, and Law Reform, on Medically Assisted Dying [PDF]
, 1993 Traditional medical ethics and law draw a sharp distinction between allowing a patient to die and helping her die. Withholding or withdrawing life sustaining treatment, such as by abating technological nutrition, hydration or respiration, will cause ...
Gostin, Lawrence O.
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source