Results 171 to 180 of about 597,603 (289)

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Recent developments in applied microbiology and biochemistry /

"Touching all areas of microbiology, Recent Developments in Applied Microbiology and Biochemistry provides understanding to the application-oriented microbial concepts and updates the knowledge with recent developments on related aspects of both ...
Viswanath, Buddolla,editor.
core  

Greetings from foodland: teaching food and nutrition biochemistry to undergraduates in Italy

, 2017
CONTEXT. Biochemistry have always been a mandatory topic within undergraduate courses at UNIMI aimed at food/nutrition students, namely: Food Science & Technology (BS and MS); Catering Sciences (BS); Human Nutrition (MS).
F. Bonomi, M. Marengo, A. Barbiroli, S. Iametti   +3 more
core  

National recommendations of the Working Group for Post-analytics of the Croatian Society of Medical Biochemistry and Laboratory Medicine: implementation of autovalidation procedures. [PDF]

Biochem Med (Zagreb)
Rimac V, Vlašić Tanasković J, Jokić A, Honović L, Podolar S, Leniček Krleža J.   +5 more
europepmc   +1 more source

‘Relevance’ in the medical biochemistry course

Academic Medicine, 1971
openaire   +3 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Attitudes toward plagiarism among pharmacy and medical biochemistry students – cross-sectional survey study

, 2010
Introduction: Plagiarism is one of the most frequent and serious forms of misconduct in academic environment. The cross-sectional survey study was done with aim to explore the attitudes toward plagiarism.
Martina Mavrinac, Vanja Pupovac, Pupovac, Vanja, Lidija Bilic-Zulle, Mladen Petrovecki, Petrovecki, Mladen, Bilic-Zulle, Lidija, Mavrinac, Martina   +7 more
core   +1 more source

National recommendations of the Working group for laboratory diagnostics of autoimmune diseases of the Croatian Society of Medical Biochemistry and Laboratory Medicine: Assessment of antineutrophil cytoplasmic antibodies (ANCA). [PDF]

Biochem Med (Zagreb)
Kozmar A, Tešija Kuna A, Tomić Sremec N, Đerek L, Drvar V, Gugo K.   +5 more
europepmc   +1 more source

Biochemistry for Medical Students [PDF]

Journal of Clinical Pathology, 1971
openaire   +1 more source