Results 41 to 50 of about 5,691,277 (301)

Acute toxicity of ADB‐CHMINACA ‐ a case series of patients with pronounced central nervous symptoms including the posterior reversible encephalopathic syndrome

British Journal of Clinical Pharmacology, EarlyView.
Aim This report presents a series of 16 patients who were admitted to the emergency department following confirmed intake of the potent synthetic cannabinoid ADB‐CHMINACA. Methods The cases are drawn from a prospective observational study following the recreational use of synthetic cannabinoids.
Maren Hermanns‐Clausen, Michaela Sommer, Annette Zschiesche, Verena Angerer, Martin Scheu, Florian Eyer, Johannes Nadler, Volker Auwärter   +7 more
wiley   +1 more source

Cannabidiol’s cytotoxicity in pancreatic cancer is induced via an upregulation of ceramide synthase 1 and ER stress

Journal of Cannabis Research
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most aggressive malignancies with a median 5 year-survival rate of 12%. Cannabidiol (CBD) has been found to exhibit antineoplastic potential and may potentiate the anticancer effects of cytotoxic’
Nagina Mangal, Vikash Reebye, Nagy Habib, Mikael H. Sodergren   +3 more
doaj   +1 more source

High-CBD Extract (CBD-X) in Asthma Management: Reducing Th2-Driven Cytokine Secretion and Neutrophil/Eosinophil Activity

Pharmaceuticals
Background/Objectives: Asthma is a chronic inflammatory disorder of the airways affecting over 10% of the global population. It is characterized by airway inflammation, mucus hypersecretion, and bronchial hyperresponsiveness, driven predominantly by type
Miran Aswad, Antonina Pechkovsky, Narmeen Ghanayiem, Haya Hamza, Yaniv Dotan, Igal Louria-Hayon   +5 more
doaj   +1 more source

Evaluation of Patient Reported Safety and Efficacy of Cannabis From a Survey of Medical Cannabis Patients in Canada

Frontiers in Public Health, 2021
With the medical use of cannabis permitted in Canada since 2001, patients seek to use this botanical drug to treat a range of medical conditions. However, many healthcare practitioners express the need for further scientific evidence around the use of ...
Shaina P. Cahill, Stephanie E. Lunn, Patrick Diaz, Jonathan E. Page, Jonathan E. Page   +4 more
doaj   +1 more source

IPU: Medical cannabis update. [PDF]

, 2019
In this article, Pamela Logan, Director of Pharmacy Services, IPU, gives an update on access to medical cannabis in Ireland. Licence for cannabis In Ireland Cannabis is classified as a Controlled Drug, Schedule 1 (with a few exceptions), which means
Logan, Pamela
core  

Exploring new avenues: Psychedelic‐assisted therapy for young people

British Journal of Clinical Pharmacology, EarlyView.
Rates of mental illness in young people are increasing, whereas the development of novel mental health treatments has not significantly progressed. Psychedelic‐assisted therapy, using substances such as psilocybin and 3,4‐methylenedioxymethamphetamine (MDMA), has shown potential in the treatment of mental illnesses in the adult population, including ...
Ioanna Artemis Vamvakopoulou, Dasha Nicholls, David J. Nutt, Martina Di Simplicio   +3 more
wiley   +1 more source

Assessment of clinical outcomes in patients with fibromyalgia: Analysis from the UK Medical Cannabis Registry

Brain and Behavior, 2023
Introduction : There are limited therapeutic options for individuals with fibromyalgia. The aim of this study is to analyze changes in health‐related quality of life and incidence of adverse events of those prescribed cannabis‐based medicinal products ...
Claire Wang, Simon Erridge, Carl Holvey, Ross Coomber, Azfer Usmani, Mohammed Sajad, Rahul Guru, Wendy Holden, James J. Rucker, Michael W. Platt, Mikael H. Sodergren   +10 more
doaj   +1 more source

Exploring medical cannabis use in individuals with a traumatic brain injury

Exploration of Medicine, 2023
Aim: Traumatic brain injury (TBI) is a common neurological condition, which can present with a wide range of neuropsychological symptoms. Treating this broad spectrum of symptoms represents a significant medical challenge.
Elizabeth N. R. Schjelderup, Caroline A. MacCallum, Lindsay A. Lo, Jessie Dhillon, April Christiansen, Carly Pistawka, Kathryn Rintoul, William J. Panenka, Alasdair M. Barr   +8 more
doaj   +1 more source

An ETH‐LAD trip with unfavourable consequences: A case report

British Journal of Clinical Pharmacology, EarlyView.
Numerous analogues of the psychedelic and internationally controlled hallucinogen LSD have been described; however, only a limited number have been systematically investigated. This report presents the first case with an analytically confirmed ingestion of ETH‐LAD (6‐ethyl‐6‐nor‐lysergic acid diethylamide), the N‐ethyl derivative of LSD.
Johannes Nadler, Michaela Sommer, Annette Zschiesche, Anne Stürzebecher, Christina Grumann, Volker Auwärter, Maren Hermanns‐Clausen   +6 more
wiley   +1 more source

Cannabigerol (CBG) Modulates Neutrophil Activity and Ameliorates Rheumatoid Arthritis Pathogenesis

Pharmaceuticals
Background/Objectives: Rheumatoid arthritis (RA) is a chronic, inflammatory, autoimmune disease that primarily affects the joints. Current treatments aim to relieve pain and limit joint damage; however, many are associated with significant side effects ...
Miran Aswad, Antonina Pechkovsky, Haya Hamza, Igal Louria-Hayon   +3 more
doaj   +1 more source