Results 141 to 150 of about 5,415,162 (331)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Factors influencing the career preferences of medical students and interns: a cross-sectional, questionnaire-based survey from India

Journal of Educational Evaluation for Health Professions, 2019
Purpose The study aimed to identify the motivational factors and demographic variables influencing the career preferences of medical students and interns in India.
R. Anand, P. Sankaran
semanticscholar   +1 more source

Flipped classroom for academic and career advising: an innovative technique for medical student advising [PDF]

, 2018
Introduction: Career advising for medical students can be challenging for both the student and the adviser. Our objective was to design, implement, and evaluate a "flipped classroom" style advising session.
Kathy Smith, Siwik, Violet P., Smith, Kathy W., Brady Laughlin, George Fantry, William Adamas-Rappaport, Amini, Richard, Laughlin, Brady S., Adamas-Rappaport, William J., Violet Siwik, Fantry, George T., Richard Amini   +11 more
core   +1 more source

The trajectory and transition pattern of intention to practice medicine among medical students in China

Heliyon
There has been a growing concern about the career intentions (whether medical students have the intention to practice medicine) due to the increasingly serious problem of medical students attrition. Career intentions have the potential to promote medical
Zehua Shi, Hongbin Wu
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

The medical career choice motivations — Results from a Hungarian study

, 2011
Some decades ago being a medical doctor was characterized unambiguously as a profession that offers help and serves the patients’ needs during medical treatment. In today’s society, this image of the medical profession has been substantially changed. The
Edmond Girasek, Regina Molnár, E. Eke, M. Szócska   +3 more
semanticscholar   +1 more source

Developing New Zealand’s medical workforce: Realising the potential of longitudinal career tracking [PDF]

, 2019
For over a decade, the Medical Schools Outcomes Database and Longitudinal Tracking Project (MSOD) has collected data from medical students in Australia and New Zealand.
Smith, B, Hyland, F, Kool, Bridget, Jo, Conwoo, Poole, Phillippa, Roberts, E, Wilkinson, TJ, Bagg, Warwick, Freegard, J, Verstappen, Antonia, Rudland, J   +10 more
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

The relationship between socioeconomic status and the career calling of medical students: the chain mediation effect of social support and subjective social status

BMC Medical Education
Purpose To improve the career calling of medical students and cultivate high-quality medical workers, this study aimed to investigate the role of socioeconomic status in the career calling of medical students. Methods The questionnaire method was used to
Xiaoguang Wu, Tangwen Wang, Siyu Di
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source