Results 161 to 170 of about 5,415,162 (331)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Changes Needed in the Training and Education of the Increasing Numbers of Female Medical Students [PDF]

open access: yes, 2011
Women’s educational opportunities have been increasing and women’s general advancement in higher education is the underlying factor behind the increasing number of female students in medical school. A number of issues affect female students and residents,
연세대학교 의과대학
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

La interdisciplinariedad, una experiencia desde la disciplina Informática Médica con enfoque filosófico

open access: yesRevista Habanera de Ciencias Médicas
Introducción: la interdisciplinariedad como tendencia de la educación superior a nivel mundial, es acogida por la educación médica cubana, lo cual se manifiesta en el diseño curricular.
Odalys Blanco Aspiazu   +2 more
doaj  

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

The employment gap: the relationship between medical student career choices and the future needs of the New Zealand medical workforce [PDF]

open access: yes, 2019
Aim To determine the career decision intentions of graduating doctors, and the relationship between these intentions and the predicted medical workforce needs in New Zealand in 10 years’ time.
Wilkinson, T   +7 more
core  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

The Net Present Value and Other Economic Implications of a Medical Career.

open access: yesAcademic medicine : journal of the Association of American Medical Colleges, 2017
U. Reinhardt
semanticscholar   +1 more source

The Making of Medical College System and Medical Education under Japanese Rule, 1916-1945 [PDF]

open access: yes, 2017
Medical education and research under Japanese rule characterize the construction and cracking of medical college system. It was Keijo Medical College(KMC) and Severance Union Medical College(SUMC) that led the construction of the colonial medical college
신규환
core  

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