Results 201 to 210 of about 7,272,574 (261)

Perceptions of digital medical information services applying new technologies. [PDF]

J Med Libr Assoc
Lee GE, Seo J, Choi YJ, Lee JY.
europepmc   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Causal spectral segmenter: counterfactual graph reasoning for weakly supervised pathology segmentation. [PDF]

Bioinformatics
Zhang X, Si J, Lu W, Li C, Zhang X.
europepmc   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Editorial: Advancing human wellbeing: environment-focused AI technologies. [PDF]

Front Artif Intell
Idrissi N, Roche M, Gaba GS, Sadqi Y, Erritali M.   +4 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Big Data Analytics Framework for Early Breast Cancer Detection Using Optimized MapReduce and Deep Learning on Large-Scale Mammographic Data. [PDF]

Int J Biomed Imaging
Ahmed MM, Hassanien E.
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Increasing value in the Veterans Affairs Healthcare System (VA) with precision health: a continuing landmark collaboration with the Department of Energy. [PDF]

J Am Med Inform Assoc
Justice AC, McMahon B, Jacobson DA, Cho K, Kapadia AJ, Aguayo SM, Gümüş ZH, Danciu I, Beckham JC, Kimbrel NA, Crivelli S, Boudreau EA, Finley P, Bryant AK, Green M, Yoo S, Joseph J, Reaven P, Zhou J, Luoh SW, Madduri R, Fanous A, Agarwal K, Mukundan H, Muralidhar S.   +24 more
europepmc   +1 more source