Results 111 to 120 of about 10,137,565 (351)

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Artificial Neural Network, Attention Mechanism and Fuzzy Logic-Based Approaches for Medical Diagnostic Support: A Systematic Review

AI
Accurate medical diagnosis is essential for informed decision making and the delivery of effective treatment. Traditionally, this process relies on clinical judgment, integrating data and medical expertise to inform decision making.
Noel Zacarias-Morales, Pablo Pancardo, José Adán Hernández-Nolasco, Matias Garcia-Constantino   +3 more
doaj   +1 more source

An Improved Correlation Coefficient of Intuitionistic Fuzzy Sets

Journal of Intelligent Systems, 2019
The intuitionistic fuzzy set is a useful tool to deal with vagueness and uncertainty. Correlation coefficient of the intuitionistic fuzzy sets is an important measure in intuitionistic fuzzy set theory and has great practical potential in a variety of ...
Huang Han-Liang, Guo Yuting
doaj   +1 more source

Neutrosophic Topological Spaces for Lung Cancer Detection in Chest X-Rays: A Novel Approach to Uncertainty Management [PDF]

Neutrosophic Sets and Systems
Decision-making in medical diagnosis is often hampered by uncertainties due to incomplete, ambiguous, and evolving information. In reviewing the traditional methods for lung cancer detection, we found that crisp and logic values have more difficulties ...
A. A. Salama, Doaa E. Mossa, Mahmoud Y. Shams, Huda E. Khalid, Ahmed K. Essa   +4 more
doaj   +1 more source

An Alternative Medical Diagnosis Method: Biosensors for Virus Detection

Biosensors, 2019
Infectious diseases still pose an omnipresent threat to global and public health, especially in many countries and rural areas of cities. Underlying reasons of such serious maladies can be summarized as the paucity of appropriate analysis methods and ...
Yeşeren Saylan, Özgecan Erdem, S. Ünal, A. Denizli   +3 more
semanticscholar   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

A Hybrid Decision Making Framework with Pythagorean Fuzzy Information for Childhood Cancer Prognosis [PDF]

Sahand Communications in Mathematical Analysis
Medical information is complex and confidential, making accurate diagnosis challenging, especially with varying expert opinions. This study proposes a hybrid multicriteria decision-making (MCDM) approach combining the Pythagorean fuzzy method based on ...
Naveen Kumar, Juthika Mahanta
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Fault Tolerant Neural Network for ECG Signal Classification Systems

Advances in Electrical and Computer Engineering, 2011
The aim of this paper is to apply a new robust hardware Artificial Neural Network (ANN) for ECG classification systems. This ANN includes a penalization criterion which makes the performances in terms of robustness.
MERAH, M., OUAMRI, A., NAIT-ALI, A., KECHE, M.   +3 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source