Purulent Nasal Discharges: their Diagnosis and Treatment. By Tilley Herbert, M.D., B.S. Lond., F.R.C.S. Eng. The Medical Publishing Company, Ltd. [PDF]
, 1900 Dandas Grant
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Short-Term cost impact of compliance with clinical practice guidelines for initial sarcoma treatment [PDF]
Background: The impact of compliance to clinical practice guidelines (CPG) on outcomes and/or costs of care has not been completely clarified.Objective: To estimate relationships between medical expenditures and compliance to CPG for initial sarcoma ...
Anne-Valérie Decouvelaere +17 more
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ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma
Molecular Oncology, EarlyView.In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee +9 more
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EARLY SYMPTOMS AND DIAGNOSIS OF TUBERCULAR JOINT DISEASE.Read in the Section on Surgery and Anatomy at the Forty-fifth Annual Meeting of the American Medical Association, held at San Francisco, June 5-8, 1894. [PDF]
, 1894 Emmet Rixford
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Molecular Oncology, EarlyView.This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima +6 more
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A CLINICAL TEXT-BOOK OF MEDICAL DIAGNOSIS for Physicians and Students, Based on the Most Recent Methods of Examination [PDF]
, 1891 OSWALD VIERORDT, Francis H. Stuart
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Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Molecular Oncology, EarlyView.Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides +13 more
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THE GRAPHOPHONE IN MEDICINE: A NEW ADDITION TO MEDICAL ART IN DIAGNOSIS. [PDF]
, 1889 Benjamin Ward Richardson
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Molecular Oncology, EarlyView.Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova +26 more
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The Medical Check-up or Pre-symptomatic Diagnosis [Abridged] [PDF]
, 1963 R. R. Bomford
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