Results 131 to 140 of about 8,468,863 (266)

The clinical value of pharmacogenomics in the pharmacotherapy of common psychiatric disorders: a macroscopic analysis based on real-world data

BMC Psychiatry
Background Pharmacogenomic (PGx) testing holds promise for personalized psychiatry, but its clinical utility in real-world inpatient settings remains inadequately established.
Fei Jia, Yanjie Zhao, Shanshan Tian, Nan Wang, Xiaoqian Lan, Mengxi Niu, Shuang Bao, Yannan Zang, Linghui Meng, Pengfei Li, Gang Wang   +10 more
doaj   +1 more source

Food Insecurity Among College Students with and without Medical Disorders at a University in Appalachia. [PDF]

J Appalach Health, 2020
McArthur LH, Gutschall M, Fasczewski KS, Jackson A.   +3 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Interaction between BDNF Val66Met polymorphism and mismatch negativity for working memory capacity in schizophrenia

Schizophrenia
Both the brain-derived neurotrophic factor (BDNF) valine (Val)/methionine (Met) polymorphism and mismatch negativity (MMN) amplitude are reportedly linked to working memory impairments in schizophrenia.
Wenpeng Hou, Xiangqin Qin, Hang Li, Qi Wang, Yushen Ding, Xiongying Chen, Ru Wang, Fang Dong, Qijing Bo, Xianbin Li, Fuchun Zhou, Chuanyue Wang   +11 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

LC–MS/MS quantification of 20(S)-protopanaxadiol in complex biological matrices for bioanalytical method validation and pharmacokinetic analysis

Scientific Reports
20(S)-Protopanaxadiol (PPD) is a saponin derivative of ginsenoside, with more potent biological and pharmacological activities than Rg3 and Rh2. The lack of ionizable centers leads to low mass spectrometry reactions and internal cleavage of three ...
Pengfei Li, Shanshan Liu, Hongyan Zhuang, Mengxi niu, Fei Pan, Nan Wang, Sha Sha, Qian Wang, Jing Wang   +8 more
doaj   +1 more source

Severe mental illness and health service utilisation for nonpsychiatric medical disorders: A systematic review and meta-analysis. [PDF]

PLoS Med, 2020
Ronaldson A, Elton L, Jayakumar S, Jieman A, Halvorsrud K, Bhui K.   +5 more
europepmc   +1 more source

Medical Center grounds diagram

This glass lantern slide features a black and white diagram of the Medical College of South Carolina Medical Center ...
Medical College of South Carolina (1952-1969). Department of Medical Illustration
core  

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Attentional bias abnormalities and their association with cognitive load in obsessive-compulsive disorder

BMC Psychiatry
Background Attentional bias is a significant factor in the onset and persistence of obsessive-compulsive symptoms in individuals with obsessive-compulsive disorder (OCD). However, the determinants of attentional bias in OCD remain inadequately understood.
Zijun Yan, Xu Ma, Si Mi, Xiangyun Yang, Jinyu Zhang, Yu Chen, Danfeng Yuan, Pengchong Wang, Zhanjiang Li   +8 more
doaj   +1 more source