Results 171 to 180 of about 8,468,863 (266)

Executive functioning profiles from the BRIEF across pediatric medical disorders: Age and diagnosis factors. [PDF]

Child Neuropsychol, 2016
Krivitzky LS, Walsh KS, Fisher EL, Berl MM.   +3 more
europepmc   +1 more source

Medical College Hospital bridge

This glass lantern slide features a ground view of the bridge extending from the Medical College of South Carolina ...
Medical College of South Carolina (1952-1969). Department of Medical Illustration
core  

Medical College Hospital, April 3, 1955

, 1955
This glass lantern slide features a ground view of the Medical College of South Carolina Hospital in April of ...
Medical College of South Carolina (1952-1969). Department of Medical Illustration
core  

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Pharmacotherapy for alcohol use disorder among adults with medical disorders in Sweden. [PDF]

Addict Sci Clin Pract
Månsson A, Danielsson AK, Sjöqvist H, Glatz T, Lundin A, Wallhed Finn S.   +5 more
europepmc   +1 more source

Screening of Patients with Chronic Medical Disorders in the Outpatient Department for Depression Using Handheld Computers as Interface and Patient Health Questionnaire-9 as a Tool. [PDF]

Int J Appl Basic Med Res, 2017
Ingle VK, Pandey I, Singh AR, Singh AR, Pakhare A, Kumar S.   +5 more
europepmc   +1 more source

Bridge to Medical College from hospital construction, 1953

, 1953
This glass lantern slide features an aerial view of the bridge to the Medical College building from the Medical College of South Carolina Hospital during its construction in ...
Medical College of South Carolina (1952-1969). Department of Medical Illustration
core  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source