Results 151 to 160 of about 4,232,046 (375)

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

open access: yesMolecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim   +8 more
wiley   +1 more source

O relatório Flexner: para o bem e para o mal

open access: yesRevista Brasileira de Educação Médica
Às vésperas de completar cem anos de publicação, o Relatório Flexner e a figura de seu autor são, até hoje, foco de debates e polêmica. Neste artigo, discutem-se os aportes de Abraham Flexner para a educação médica a partir da publicação de seu relatório,
Fernando Luiz Pagliosa   +1 more
doaj   +1 more source

3D Modelling to Address Pandemic Challenges: A Project-Based Learning Methodology [PDF]

open access: yesarXiv
The use of 3D modelling in medical education is a revolutionary tool during the learning process. In fact, this type of technology enables a more interactive teaching approach, making information retention more effective and enhancing students' understanding.
arxiv  

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

GenAI Assisting Medical Training [PDF]

open access: yesarXiv
Medical procedures such as venipuncture and cannulation are essential for nurses and require precise skills. Learning this skill, in turn, is a challenge for educators due to the number of teachers per class and the complexity of the task. The study aims to help students with skill acquisition and alleviate the educator's workload by integrating ...
arxiv  

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

Integração Curricular a partir da Análise de uma Disciplina de um Curso de Medicina

open access: yesRevista Brasileira de Educação Médica
RESUMO A análise de práticas curriculares tem sido uma atividade cada vez mais presente nas produções científicas no campo do currículo, sobretudo porque nelas se coadunam as relações estabelecidas entre o conhecimento, o currículo prescrito e sua ...
Jaqueline Santos Barboza   +1 more
doaj   +1 more source

Analysis of the Institutional Free Market in Accredited Medical Physics Graduate Programs [PDF]

open access: yesarXiv
Medical Physics education is delivered through accredited programs with admissions and funding for students determined by individual institutions providing the educational experiences. Public data from accredited graduate programs, along with funding data, were used to analyze institutional trends in this educational market.
arxiv  

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