Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park+6 more
wiley +1 more source
Book Review - Do No Harm: Stories of Life, Death and Brain Surgery
In the present article, we review the book Do No Harm: Stories of Life, Death and Brain Surgery, by British neurosurgeon Dr. Henry Marsh, a book that can offer a significant contribution to medical education regarding the ethics and vocation for ...
Gilvan Aguiar da Silva+1 more
doaj +1 more source
"انعكاس الأخطاء الطبية في المستشفيات الفلسطينية على الأسرة والمجتمع، دراسة من وجهة نظر أسر الضحايا في جنوب الضفة الغربية من العام 2010 لغاية 2016" [PDF]
This study aims at revealing the most important negative social effects of the medical errors on the families' victims. It also identifies the reactions of those medical errors on the Palestinian community in the southern part of West Bank.This study ...
عكة, محمد
core
Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren+4 more
wiley +1 more source
Pediatric Nurse Practitioner Home Visitation is Associated with a Decrease in Home Care and Healthcare Utilization Errors in High Risk Infants [PDF]
The Santa Clara Valley Health and Hospital System’s (SCVHHS) Babies Reaching Improved Development and Growth in their Environment (BRIDGE) program was developed in 2011 to optimize high risk infants\u27 care transition from Neonatal Intensive Care Unit ...
Patel, Rupalee
core +1 more source
Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song+13 more
wiley +1 more source
Criminal Liability for Multiple Medical Errors
Medical errors that result in the harm or death of patients are still a major problem in health sectors all over the world. Identifying the cause of a medical error can be a difficult task because a large number of medical procedures involve the ...
Mohammad Fathi Shahta Ebrahim+1 more
doaj +1 more source
Medical errors: Mandatory reporting, voluntary reporting, or both? [PDF]
This work evaluates policy recommendations on medical error reporting systems presented in, To err is human, a report published by the Institute of Medicine.
Grepperud, Sverre
core
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam+9 more
wiley +1 more source