Results 111 to 120 of about 1,825,467 (355)

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

open access: yesMolecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza   +3 more
wiley   +1 more source

Mistakes in medical ontologies: Where do they come from and how can they be detected? [PDF]

open access: yes, 2004
We present the details of a methodology for quality assurance in large medical terminologies and describe three algorithms that can help terminology developers and users to identify potential mistakes.
Ceusters, Werner   +3 more
core  

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

open access: yesMolecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha   +10 more
wiley   +1 more source

The Impact of Medical Simulations on Reducing Medical Errors

open access: yesJournal of Education, Health and Sport
Modern medical simulations are an effective tool for reducing medical errors by providing healthcare professionals with the opportunity to practice in a safe, controlled environment. These simulations help refine both technical and non-technical skills,
Elżbieta Leszczyńska-Knaga   +9 more
doaj   +1 more source

MEDICATION ERROR

open access: yes, 2019
A medication error is any preventable event that may cause or lead to inappropriate medication use or patient harm while medication is in the control of health care professional. (NCC, 2019).
openaire   +1 more source

Factors Associated with the Incidence of Medication Errors and Nurses' Refusal to Error Reporting [PDF]

open access: yes, 2016
Introduction:Medication errors may occur at every stage of the medicines prescription and distribution processes and as nurses can give more than 150 medicines to patients in one work shift, they are in the first line of medical errors.
Badiee,   +6 more
core  

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Engaging Students and Faculty in the Evaluation of a USMLE Review Product: Implications for Library Collection Development [PDF]

open access: yes, 2016
Introduction: Study materials for USMLE exams are some of the most commonly requested materials at Dana Medical Library. In Fall 2015, the Dana Medical Library received several student requests for online USMLE preparation materials.
Light, Jeanene, Stokes, Alice
core   +1 more source

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