Results 71 to 80 of about 1,781,086 (356)

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Reducing Medication Errors Through Workflow Redesign [PDF]

, 2017
Lack of medication reconciliation at the point of transitions between skilled nursing facilities/nursing homes (SNF/NHs) and acute care hospitals (ACHs) is a common point of origin for medical errors that cause harm to patients.
Blake, Rosslyn W, DNP, APRN, GNP
core   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Mistakes in medical ontologies: Where do they come from and how can they be detected? [PDF]

, 2004
We present the details of a methodology for quality assurance in large medical terminologies and describe three algorithms that can help terminology developers and users to identify potential mistakes.
Ceusters, Werner, Dhaen, Christoffel, Kumar, Anand, Smith, Barry   +3 more
core  

Errores médicos Medical Errors

Acta Médica Costarricense, 2009
El error médico es cualquier falla ocurrida durante la atención de salud que haya causado algún tipo de daño al paciente, y cuyo origen puede relacionarse con la organización e implementación del servicio, a través de múltiples y complejos mecanismos ...
Carlos Arrea-Baixench
doaj   +2 more sources

2-MEDICAL ERRORS AND RESPONSIBILITY OF THE PHYSICIAN [PDF]

Basrah Journal of Surgery, 2009
LEADING ARTICLE The physician is an active member of the society. He interacts with it, influences and takes care of it. His duty is not only to cure patients, but also to take the necessary procedures to reduce errors and to lessen the harm resulting ...
Thamer A Hamdan
doaj   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Lessons Learned: Nurses’ Experiences with Errors in Nursing [PDF]

, 2016
Background Health care organizations seek to maximize the reporting of medical errors to improve patient safety. Purpose This study explored licensed nurses' decision-making with regard to reporting medical errors.
Burke Draucker, Claire, Ebright, Patricia R., Koehn, Amy R.   +2 more
core   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

Does Medical Malpractice Law Improve Health Care Quality? [PDF]

, 2016
Despite the fundamental role of deterrence in justifying a system of medical malpractice law, surprisingly little evidence has been put forth to date bearing on the relationship between medical liability forces on the one hand and medical errors and ...
Anupam B. Jena, Atkins, Baicker, Baicker, Bovbjerg, Card, Centers for Medicare and Medicaid Services, Chan, Chandra, Conley, Crump, Currie, Currie, Dewees, Dubay, Farnsworth, Fisher, Frakes, Frakes, Hussey, Hyman, Iizuka, Jena, Kachalia, Kessler, Klick, Lakdawalla, Mello, Mello, Mello, Michael Frakes, Office of Technology Assessment, Paik, Phelps, Polinsky, Rosenbaum, Schiff, Schwartz, Seabury, Shepherd, Skinner, Sloan, Sloan, Sommers, Wennberg, Zeiler   +45 more
core   +2 more sources