Results 71 to 80 of about 1,825,467 (355)

A computer supported memory aid for copying prescription parameters into medical equipment based on linguistic phrases [PDF]

open access: yes, 2013
Manually operated medical equipment, including drug infusion pumps, are often subject to input errors. Human operators copy data from a prescription into the relevant form field on the equipment panels. This process is error prone and time consuming.
Huang, Yo-Ping, Sandnes, Frode Eika
core   +2 more sources

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

Epinephrine: Medication Error

open access: yesEurasian Journal of Emergency Medicine, 2016
Epinephrine plays an integral role in the treatment of several life treating diseases. It can be administered at different doses and through different routes of administration. Nebulized L-epinephrine has been described as a safe treatment method.
KARACAN, CAN DEMİR   +3 more
openaire   +3 more sources

"انعكاس الأخطاء الطبية في المستشفيات الفلسطينية على الأسرة والمجتمع، دراسة من وجهة نظر أسر الضحايا في جنوب الضفة الغربية من العام 2010 لغاية 2016" [PDF]

open access: yes, 2018
This study aims at revealing the most important negative social effects of the medical errors on the families' victims. It also identifies the reactions of those medical errors on the Palestinian community in the southern part of West Bank.This study ...
عكة, محمد
core  

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

Quality of medication use in primary care - mapping the problem, working to a solution: a systematic review of the literature [PDF]

open access: yes, 2009
Background: The UK, USA and the World Health Organization have identified improved patient safety in healthcare as a priority. Medication error has been identified as one of the most frequent forms of medical error and is associated with significant ...
A Hassey   +54 more
core   +4 more sources

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Speech Recognition Technology: Improving Speed and Accuracy of Emergency Medical Services Documentation to Protect Patients [PDF]

open access: yes, 2018
Because hospital errors, such as mistakes in documentation, cause one in six deaths each year in the United States, the accuracy of health records in the emergency medical services (EMS) must be improved.
Tran, Tan
core   +4 more sources

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

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