Results 91 to 100 of about 3,254,012 (312)

Environmental tobacco smoke exposure and health disparities: 8-year longitudinal findings from a large cohort of Thai adults [PDF]

open access: yes, 2015
BACKGROUND: In rich countries, smokers, active or passive, often belong to disadvantaged groups. Less is known of tobacco patterns in the developing world.
Chinwong, Dujrudee   +4 more
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Child and Youth Victimization Known to Police, School, and Medical Authorities. [PDF]

open access: yes, 2012
Presents the survey results from the National Survey of Children\u27s Exposure to Violence (NatSCEV) regarding authorities\u27 knowledge of victimization incidents involving children and youth, particularly police, school, and medical authorities ...
Finkelhor, David   +3 more
core   +1 more source

Laser-wakefield accelerators as hard x-ray sources for 3D medical imaging of human bone [PDF]

open access: yes, 2015
A bright μm-sized source of hard synchrotron x-rays (critical energy Ecrit > 30 keV) based on the betatron oscillations of laser wakefield accelerated electrons has been developed.
Abel, RL   +12 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Engaging current and potential medical students in clinical research during an elective hospital attachment: a qualitative study [PDF]

open access: yes, 2012
Session - Curriculum Planning; International Medical EducationBACKGROUND AND PURPOSE: Exposure of medical students to research may increase the probability of their pursuing postgraduate research involvement(1,2).
Clin, H, Shing, LK, Sihoe, AD
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The impact of the 2020 diagnostic reference level revision and the development of national regulations on occupational radiation protection in medical facilities in Japan

open access: yesFrontiers in Public Health
This study examined the impact of revisions to the diagnostic reference levels and the Regulation on Prevention of Ionizing Radiation Hazards on radiation safety management in medical institutions by investigating changes in the awareness of occupational
Takakiyo Tsujiguchi   +9 more
doaj   +1 more source

Medical Student Summer Externship Program: Increasing the Number Matching in Family Practice [PDF]

open access: yes, 2004
: Background and Objectives. The number of US allopathic medical school graduates choosing a residency in family medicine has fallen from 13.4% in 1999 to 10.5% in 2002.
Cronau, MD, Holly   +1 more
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy