Results 101 to 110 of about 3,286,932 (311)

The impact of the 2020 diagnostic reference level revision and the development of national regulations on occupational radiation protection in medical facilities in Japan

Frontiers in Public Health
This study examined the impact of revisions to the diagnostic reference levels and the Regulation on Prevention of Ionizing Radiation Hazards on radiation safety management in medical institutions by investigating changes in the awareness of occupational
Takakiyo Tsujiguchi, Taito Ishikawa, Taito Ishikawa, Satoshi Arakida, Taiga Kanozawa, Teru Suzuki, Hajime Sakamoto, Takeshi Sasaki, Masataka Narita, Yasuyuki Takahashi   +9 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Effect of X-ray scan quality on the collective effective dose in patients in telemedicine [PDF]

Digital Diagnostics
BACKGROUND: The key objective of a healthcare provider is to ensure the quality and increase the efficiency of X-ray diagnostics in both municipal and private medical facilities. A poor-quality radiologic image requires repeated procedures, which results
Zoya A. Lantukh, Daria D. Kozhikhina, Kirill V. Tolkachev, Maria P. Shatenok, Ilya V. Soldatov, Uliya V. Druzhinina, Yuriy A. Vasilev, Sergey A. Ryzhov, Aleksandr V. Vodovatov   +8 more
doaj   +1 more source

Medical Countermeasures for Radiation Induced Health Effects: Reports of an Interagency Panel Session Held at the NASA Human Research Program Investigator's Workshop, January 26, 2017 [PDF]

An Interagency Panel Session organized by the NASA Human Research Program Space Radiation Program Element (SRPE) was held during the NASA Human Research Program (HRP) Investigators Workshop (IWS) in Galveston, Texas on January 26, 2017 to identify ...
Carnell, Lisa S., Homer, Mary, Hoots, Keith, Meeks, Heather, Prasanna, Pataje G. S., Rios, Carmen, Simonsen, Lisa C., Taliaferro, Lanyn, Wathen, Lynne K.   +8 more
core   +1 more source

Market Access Analysis of Biologics and Small-Molecule Inhibitors for Inflammatory Bowel Disease Among US Health Insurance Policies. [PDF]

, 2019
BACKGROUND AND AIMS:Treatment pathways for ulcerative colitis (UC) and Crohn's disease (CD) are shifting to a more individualized, risk-stratified approach.
Cao, Charlie, Dulai, Parambir S, Lasch, Karen, Osterman, Mark T, Riaz, Faisal, Sandborn, William J   +5 more
core  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Occupational and Patient Doses in Interventional Cardiology in Indonesia: A Preliminary Result

Atom Indonesia, 2019
Interventional cardiology is a branch of cardiology that manages the catheter based treatment of structural heart illnesses. These minimally invasive procedures involve inserting catheters and other devices through superficial arterial and venous access ...
E. Hiswara, K.H. Ng, H. Sofyan, D. Kartikasari, N. Nuraeni   +4 more
doaj   +1 more source

Unexpected in utero exposure to psychotropic medications

European Journal of Molecular & Clinical Medicine, 2017
Introduction Pregnancies in the world each year involve women who have or who will develop psychiatric illness during the pregnancy. Psychotropics in gestation could produce adverse perinatal and postnatal outcomes, however counseling these women to discontinue medication presents new risks associated with untreated or inadequately treated mental ...
Paradiso B, Fedrigo M, Favretto D, Angelini A, Thiene G   +4 more
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source