Results 91 to 100 of about 8,826,721 (317)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Analysis of the radiation accidents prevalence in nuclear medicine in the Russian Federation
Радиационная гигиенаRadiation events (accidents) appearance is an integral part of the use of ionizing radiation sources in medicine in general and nuclear medicine in particular.
A. V. Vodovatov +6 more
doaj +1 more source
Medication Exposure and Mortality in Patients With Schizophrenia
JAMA Network OpenImportanceThe use of antipsychotics, antidepressants, and benzodiazepines may influence the risk of mortality in people with schizophrenia. However, many observational studies have not accounted for immortal time bias (ITB), which occurs when there is a period during which patients in the exposed group are necessarily alive and misclassified as exposed
Brodeur, Sébastien +10 more
openaire +2 more sources
Self-Reported Occupational Exposure to HIV and Factors Influencing its Management Practice: A Study of Healthcare Workers in Tumbi and Dodoma Hospitals, Tanzania. [PDF]
, 2013 Blood borne infectious agents such as hepatitis B virus (HBV), hepatitis C virus (HCV) and human immune deficiency virus (HIV) constitute a major occupational hazard for healthcare workers (HCWs).
Mubyazi, Godfrey M +7 more
core +2 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Радиационная гигиенаIntroduction: To successfully address the challenges of optimizing radiation protection during medical exposure, it is essential to have information on patient exposure levels and the structure of diagnostic radiology in medical organizations across the ...
A. V. Vodovatov +4 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Радиационная гигиенаThe analysis of trends in levels of radiation exposure of the public in the Russian Federation in recent years indicates a steady increase in patient doses from medical exposure.
A. V. Vodovatov +4 more
doaj +1 more source