Results 41 to 50 of about 3,286,932 (311)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Adverse Childhood Experiences in Medical Students: Implications for Wellness. [PDF]

, 2019
ObjectiveThe primary purpose of the study was to assess the prevalence of adverse childhood experiences (ACEs) in a cohort of third-year medical students and characterize their childhood protective factors.MethodsThe authors developed a web-based ...
Griffin, Erin J, Sciolla, Andrés F, Wilkes, Michael S   +2 more
core  

Deep models of integrated multiscale molecular data decipher the endothelial cell response to ionizing radiation

iScience, 2022
Summary: The vascular endothelium is a hot spot in the response to radiation therapy for both tumors and normal tissues. To improve patient outcomes, interpretable systemic hypotheses are needed to help radiobiologists and radiation oncologists propose ...
Ian Morilla, Philippe Chan, Fanny Caffin, Ljubica Svilar, Sonia Selbonne, Ségolène Ladaigue, Valérie Buard, Georges Tarlet, Béatrice Micheau, Vincent Paget, Agnès François, Maâmar Souidi, Jean-Charles Martin, David Vaudry, Mohamed-Amine Benadjaoud, Fabien Milliat, Olivier Guipaud   +16 more
doaj   +1 more source

Exposure to Maternal Medications: A Case of Lockjaw

The Canadian Journal of Hospital Pharmacy, 2013
Many infants are exposed in utero to psychoactive medications. Despite the frequency of this occurrence, there is little information regarding outcomes for these infants. In each case, the health care team must attempt to balance maternal mental health while optimizing the safety of the developing infant.
Brandi, Newby, Rebecca, Sherlock
openaire   +3 more sources

Prevalence and Trajectory of Household Material Hardship Among Children With Advanced Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Families of children with advanced cancer living in poverty experience inferior outcomes including poor parent mental health and worse child quality of life. Household material hardship (HMH: food, housing, transportation, and/or utility insecurity) is a modifiable poverty exposure—and potential intervention target—that ...
Sarah Wright, Morgan A. Paul, Selena Murcia Mendez, Emily Jones, Lucille Lokko, Chelsea Heneghan, Nicholas Purol, Morgan Arnold, Rahela Aziz‐Bose, Colleen A. Kelly, Sandi L. Pruitt, Joanne Wolfe, Kira Bona, Puja J. Umaretiya   +13 more
wiley   +1 more source

THE RESULTS OF FUNCTIONING OF THE UNIFIED SYSTEM OF INDIVIDUAL DOSE CONTROL OF THE RUSSIAN FEDERATION CITIZENS BASED ON THE 2017 DATA

Радиационная гигиена, 2018
The article presents the results of the generalized analysis of the data on staff, patient, and public doses from ionizing radiation obtained from the Unified System of Individual Dose Control for 2017.
A. N. Barkovsky, R. R. Akhmatdinov, R. R. Akhmatdinov, N. K. Baryshkov, A. M. Biblin, A. A. Bratilova, V. E. Zhuravleva, T. A. Kormanovskaya, S. I. Kuvshinnikov, I. K. Romanovich, A. G. Sivenkov, O. E. Tutelyan, A. G. Tsovyanov   +12 more
doaj   +1 more source

Financial Burden Associated With Hospitalisation Among Families of Childhood Brain Tumours in Australia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Families of children with cancer experience significant financial strain, even with universal healthcare. Indirect costs, such as productivity losses and non‐medical expenses, are rarely included in economic evaluations, and little is known about how effectively financial aid programmes alleviate this burden. Childhood brain tumours
Megumi Lim, Natalie Bradford, David Brain, Sameera Senanayake, Sanjeewa Kularatna, Kate Young, Christine Cashion, Tim Hassall, Susanna Cramb   +8 more
wiley   +1 more source

Modern principles of the radiation protection from sources of ionizing radiation in medicine. Part 1: Trends, structure of x-ray diagnostics and doses from medical exposure

Радиационная гигиена, 2019
Implementation of modern highly informative methods of X-ray diagnostics (computed tomography, interventional examinations, nuclear medicine), associated with the increase of doses to the public and patients, requires the development and improvement of ...
G. G. Onischenko, A. Yu. Popova, I. K. Romanovich, A. V. Vodovatov, N. S. Bashketova, O. A. Istorik, L. A. Chipiga, I. G. Shatsky, L. V. Repin, A. M. Biblin   +9 more
doaj   +1 more source

Understanding practitioner professionalism in Aboriginal and Torres Strait Islander health: lessons from student and registrar placements at an urban Aboriginal and Torres Strait Islander primary health care service [PDF]

, 2017
Aboriginal and Torres Strait Islander peoples continue to be pathologised in medical curriculum, leaving graduates feeling unequipped to effectively work cross-culturally.
Askew, D, Ewen, S, Lyall, V, Paul, D, Wheeler, M   +4 more
core   +1 more source

Inpatient Food Insecurity and Pediatric Hematology Oncology Hospitalization Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Children with cancer and blood disorders are at risk for food insecurity (FI). We aimed to describe the association of inpatient food insecurity (IFI) and hospitalization outcomes among patients admitted to the pediatric hematology oncology service. Of 325 caregivers screened for IFI, 60 (18.6%) screened positive.
Joanna M. Robles, Greg Russell, Leila H. DeWitt, Kimberly Montez, Callie L. Brown   +4 more
wiley   +1 more source