Results 151 to 160 of about 1,448,347 (316)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Minutes: Medical School Faculty Advisory Council, Feb. 5, 2002

, 2002
Faculty advisory council to the Dean of the Medical School.University of Minnesota. Medical School Faculty Advisory Council. (2002). Minutes: Medical School Faculty Advisory Council, Feb. 5, 2002. Retrieved from the University Digital Conservancy, https:/
University of Minnesota. Medical School Faculty Advisory Council
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Minutes: Medical School Faculty Advisory Council, Sept. 6, 2005

, 2005
Faculty advisory council to the Dean of the Medical School.University of Minnesota. Medical School Faculty Advisory Council. (2005). Minutes: Medical School Faculty Advisory Council, Sept. 6, 2005. Retrieved from the University Digital Conservancy, https:
University of Minnesota. Medical School Faculty Advisory Council
core  

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Impact of a Wellness Leadership Intervention on the Empathy, Burnout, and Resting Heart Rate of Medical Faculty. [PDF]

Mayo Clin Proc Innov Qual Outcomes, 2023
Gilin DA, Anderson GG, Etezad S, Lee-Baggley D, Cooper AM, Preston RJ.   +5 more
europepmc   +1 more source

Improved utilization of medical faculty

Academic Medicine, 1969
openaire   +3 more sources

Minutes: Medical School Faculty Advisory Council, Dec. 6, 2005

, 2005
Faculty advisory council to the Dean of the Medical School.University of Minnesota. Medical School Faculty Advisory Council. (2005). Minutes: Medical School Faculty Advisory Council, Dec. 6, 2005. Retrieved from the University Digital Conservancy, https:/
University of Minnesota. Medical School Faculty Advisory Council
core  

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Sponsorship and Career Advancement for Asian Medical Faculty. [PDF]

JAMA Netw Open
Sebastian D, Gonzalez Herrera K, Ranganathan M, Landeros-Weisenberger A, Latimore D.   +4 more
europepmc   +1 more source