Results 211 to 220 of about 74,228 (295)

Information retrieval or document retrieval? Terminological confusions and unrealistic goals in information science, exemplified in relation to generative artificial intelligence

open access: yesJournal of the Association for Information Science and Technology, Volume 77, Issue 5, Page 714-726, May 2026.
Abstract ChatGPT and related technologies have revived an old issue in information science (IS) concerning information retrieval (IR) versus document retrieval. Since 1950, the term IR has primarily been used as a misnomer for document retrieval. This problematic terminology reflects a desire to go beyond documents and provide, in response to user ...
Birger Hjørland
wiley   +1 more source

Integrating a pilot study and large trial into one adaptive design. [PDF]

open access: yesContemp Clin Trials
Dai J   +4 more
europepmc   +1 more source

Pharmacokinetics of dolutegravir, tenofovir and lamivudine during venous–venous extracorporeal membrane oxygenation (VV‐ECMO): A case report

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 5, Page 1487-1492, May 2026.
While providing potentially life‐saving cardiorespiratory support for critically ill patients, extracorporeal membrane oxygenation (ECMO) may detrimentally affect pharmacokinetic (PK) performance and concurrent drug efficacy and safety. We describe a patient with Pneumocystis jirovecii pneumonia (PJP) in the context of acquired immunodeficiency ...
Tom C. Zwart   +7 more
wiley   +1 more source

Medical Futility.

open access: yesThe Permanente journal
Kate, Scannell, Stephen C, Henry
openaire   +1 more source

Modern Clinical Trials: Seamless Designs and Master Protocols

open access: yesCancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Background Drug development is often inefficient, costly and lengthy, yet it is essential for evaluating the safety and efficacy of new interventions. Compared with other disease areas, this is particularly true for Phase II/III cancer clinical trials where many drug candidates fail to advance and reduced regulatory approvals are being seen ...
Abigail Burdon   +5 more
wiley   +1 more source

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