Results 201 to 210 of about 74,228 (295)

Design Considerations for a Phase II Platform Trial in Major Depressive Disorder. [PDF]

open access: yesPharm Stat
Freitag MM   +8 more
europepmc   +1 more source

Management of Adult Patients With Isocitrate Dehydrogenase‐Mutant Gliomas in Australia: An Expert Position Statement From the Cooperative Trials Group for Neuro‐Oncology

open access: yesAsia-Pacific Journal of Clinical Oncology, Volume 22, Issue 3, Page 392-403, June 2026.
Following maximal surgery when feasible, management of adult patients with isocitrate dehydrogenase (IDH)‐mutant glioma is complex and should be considered in a neuro‐oncology multidisciplinary context balancing disease control versus potential treatment‐associated toxicities. Options include continued surveillance, radiation therapy, chemotherapy, and/
Mark B. Pinkham   +7 more
wiley   +1 more source

A Remote Chronic Disease Management Program to Improve Cardiovascular and Metabolic Outcomes in a Diverse Community‐Based Diabetic Population: Study Design of the TAMIS Trial

open access: yesJournal of Evaluation in Clinical Practice, Volume 32, Issue 4, June 2026.
ABSTRACT Introduction Cardiovascular and cerebrovascular diseases are projected to expand in the coming decades as the main cause of death. This study outlines the escalating burden of cardiovascular diseases in low‐ and middle‐income countries (LMICs), particularly in Latin America (LA), which is expected to surpass that of other high‐population ...
Renato de Carvalho Barros   +22 more
wiley   +1 more source

Geriatric Residents' Perceptions of Training for Good Dying: A Qualitative Case Study in Colombia

open access: yesThe Clinical Teacher, Volume 23, Issue 3, June 2026.
ABSTRACT Introduction Death is a universal phenomenon influenced by cultural, social and religious factors. Despite its relevance to medical practice, geriatric residents often lack formal education on how to support patients in the dying process. Methods A qualitative case study design was conducted at a tertiary care hospital in Bogotá, Colombia ...
Cristian Camilo Llano Ceballos   +3 more
wiley   +1 more source

Current and Ongoing Clinical Studies. [PDF]

open access: yesMuscle Nerve
Abrahao A, Zinman L, Apple S.
europepmc   +1 more source

Unraveling the Dynamics of Oxytocin in Hypothalamic Neurons

open access: yesTraffic, Volume 27, Issue 2, June 2026.
Oxytocin (OT) plays an important role in regulating social behavior, and dysregulation of the oxytocinergic system leads to social impairments, such as autism spectrum disorder. Central OT release is poorly understood. Using live‐cell imaging to track vesicle trajectories, combined with machine learning‐based classification, the analysis reveals ...
Beatriz Aznar‐Escolano   +6 more
wiley   +1 more source

The Effect of Heterogeneous Definitions of Massive Transfusion on Using Blood Component Thresholds to Predict Futility in Severely Bleeding Trauma Patients. [PDF]

open access: yesJ Clin Med
Thomas SJ   +23 more
europepmc   +1 more source

Characterizing the Impact of Nucleoid‐Associated Proteins on HU‐DNA Interactions by Live‐Cell Single‐Molecule Tracking

open access: yesChemPhysChem, Volume 27, Issue 9, 14 May 2026.
The nucleoid‐associated proteins Dps, H‐NS, and HU shape the bacterial chromosome in the deep stationary phase through their interactions with the nucleoid.The bacterial nucleoid undergoes extensive structural reorganization during growth, influenced by nucleoid‐associated proteins (NAPs) whose interactions and effects on nucleoid organization remain ...
D. E. H. Fuller   +5 more
wiley   +1 more source

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