Results 131 to 140 of about 1,824,761 (332)

Approach of the patient with generalized adenopathies. Importance of the didactic strategy of the study of clinical cases: a purpose of a patient with Hodgkin’s lymphoma associated with an infection with the Epstein-Barr virus

open access: yesIatreia, 2019
We present the case of a 56-year-old patient with a generalized adenomegalic syndrome who presented a mixed cellular Hodgkin’s lymphoma associated with Epstein Barr Virus.
Villegas Molina, Juan Pablo   +9 more
doaj   +1 more source

Landscape of BRAF transcript variants in human cancer

open access: yesMolecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda   +5 more
wiley   +1 more source

World polity: anatomy of and arguments for regional and global integration [PDF]

open access: yes, 2017
This article is inspired by taking sort of a medical view on the international political world2. A medical view here means that first we need to understand the anatomy of the organism that we observe, i.e. the world.
Beyer, Cornelia
core  

Can disclosure of scoring rubric for basic clinical skills improve objective structured clinical examination? [PDF]

open access: yes, 2016
Purpose: To determine whether disclosure of scoring rubric for objective basic clinical skills can improve the scores on the objective structured clinical examination (OSCE) in medical students.
Ki Hong Chang, Miran Kim, Su Jin Chae
core   +3 more sources

Evaluating Risk Taking Propensity as a Predictor of the Outcome Dimensions of Medication History Taking

open access: yesAmerican Journal of Pharmaceutical Education, 1983
Medication history taking is a commonly discussed factor in the role of the pharmacist. Effective and efficient interviewing skills are important since they can be influential in affecting the quality of the medication history. Level of risk taking has been related to many factors which affect personal interaction.
openaire   +2 more sources

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren   +16 more
wiley   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

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