Reactive arthritis in tuberculosis : a case of Poncet's disease [PDF]
Reactive arthritis and erythema are uncommon presentations of tuberculosis (TB). Reactive arthritis in tuberculosis (TB) is known as Poncet's disease, a rare aseptic form of arthritis observed in patients with active TB.
Ahmad, Zaiton+2 more
core +1 more source
Comparison of Assessment by a Virtual Patient and by Clinician-Educators of Medical Students' History-Taking Skills: Exploratory Descriptive Study [PDF]
Jean Setrakian+4 more
openalex +1 more source
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed+8 more
wiley +1 more source
Factors Associated with Tb-Hiv/Aids Co-Infection in Kedu, Central Java [PDF]
Background: TB-HIV co-infection is one of the current biggest public health challenges in the world. Although there is a breadth of information on TB-HIV co-infection among settled populations elsewhere, to our knowledge, there are no published reports ...
Kristina, T. N. (Tri )+2 more
core
The Effect of Employing Standardized Patient on History Taking Skills of Medical Students [PDF]
Introduction: Using Standardized Patient (SP) in teaching history taking provides medical students with an opportunity to learn how to communicate with patients.
Masih Saboori+2 more
doaj
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
wiley +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
Doctors’ questions as displays of understanding [PDF]
Based on German data from history-taking in doctor-patient interaction, the paper shows that the three basic syntactic types of questions (questions fronted by a question-word (w-questions), verb-first (V1) questions, and declarative questions) provide ...
Deppermann, Arnulf+1 more
core
Assessing the Impact of Standardized Patient Encounters on Students' Medical History-taking Skills in Practice. [PDF]
Zerilli T, Fidler BD, Tendhar C.
europepmc +1 more source
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source