Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Patients' Attitude towards Medical Students in a Teaching Hospital of Pakistan
Journal of Islamic International Medical College, 2014 Objective: To study patient’s attitude towards medical students on clinical clerkship rotation in a hospital Study Design: Descriptive Cross Sectional Study.
Muhammad Nadim Akbar Khan, Noor Mah Khan, Saadia Sultana
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Evaluating an app for digital medical history taking in urgent care practices: study protocol of the cluster-randomized interventional trial 'DASI'. [PDF]
BMC Prim Care, 2023 Noack EM +8 more
europepmc +1 more source
History of the Avon Longitudinal Study of Parents and Children , c.1980-2000 [PDF]
, 2012 Annotated and edited transcript of a Witness Seminar held on 24 May 2011. Introduction by Professor David Gordon, World Federation for Medical Education.Annotated and edited transcript of a Witness Seminar held on 24 May 2011.
Overy, C, Reynolds, LA, Tansey, EM
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Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Carney complex- why thorough medical history taking is so important - report of three cases and review of the literature. [PDF]
Endocrine, 2023 Harbeck B +2 more
europepmc +1 more source
Public Health in the 1980s and 1990s: Decline and rise? [PDF]
, 2006 Annotated and edited transcript of a Witness Seminar held on 12 October 2004. Introduction by Professor Virginia Berridge, London School of Hygiene and Tropical Medicine.First published by the Wellcome Trust Centre for the History of Medicine at UCL ...
Berridge, V, Christie, DA, Tansey, EM
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Online medical history taking course: Opportunities and limitations in comparison to traditional bedside teaching. [PDF]
GMS J Med Educ, 2022 Lange S +8 more
europepmc +1 more source
The combinatorics of tastes and humours in classical Indian medicine and mathematics [PDF]
, 2000 This paper explores some combinatoric problems which are treated in the Sanskrit literature of both ayurveda (medicine) and of jyothsastra (mathematics)
Wujastyk, D
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