Results 151 to 160 of about 2,598,165 (339)
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Mental health - a medical history-taking taboo? [PDF]
Br Dent J, 2022 Radia S.
europepmc +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Risk factors for hospitalization among adults with asthma: the influence of sociodemographic factors and asthma severity. [PDF]
, 2001 BackgroundThe morbidity and mortality from asthma have markedly increased since the late 1970s. The hospitalization rate, an important marker of asthma severity, remains substantial.MethodsIn adults with health care access, we prospectively studied 242 ...
Blanc, PD +4 more
core
4.75 Social History Taking Across the Developmental Spectrum: Exposing First-Year Medical Students to Pediatric Patients [PDF]
, 2023 Nicole Cotton, Latasha Bogues
openalex +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Intermittent Leave and Reduced Schedule Leave Under the Family and Medical Leave Act [PDF]
, 2005 The Family and Medical Leave Act of 1993 (FMLA) permits workers who meet certain conditions to take up to 12 weeks per year of unpaid leave for medical or family care reasons.
Workplace Flexibility 2010, Georgetown University Law Center
core +1 more source
The Effect of Employing Standardized Patient on History Taking Skills of Medical Students [PDF]
مجله ایرانی آموزش در علوم پزشکی, 2010 Introduction: Using Standardized Patient (SP) in teaching history taking provides medical students with an opportunity to learn how to communicate with patients.
Masih Saboori +2 more
doaj