Results 101 to 110 of about 72,882 (281)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Introduction: The Critical French Medical Humanities

Essays in French Literature and Culture, 2021
In the 1990s the phenomenon known today as ‘French Cultural Studies’ emerged in the UK under the broad umbrella of French and Francophone Studies. Adopting an interdisciplinary approach, French Cultural Studies sought to open up new ways of looking at
Enda McCaffrey, Áine Larkin
doaj  

Must the Medical Subject be “Human”? Normativity, Humanism, and the Medical Humanities

, 2020
"Synapsis: A Health Humanities Journal" was founded in 2017 by Arden Hegele, a literary scholar, and Rishi Goyal, a physician. Its mission is to develop conversations among diverse people thinking about medical and humanistic ways of knowing . as a “Department Without Walls” that connects scholars and thinkers from different spheres.
openaire   +2 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Integrating health humanities in medical education: a narrative scoping review of Mazandaran University of Medical Sciences and global perspectives

Philosophy, Ethics, and Humanities in Medicine
The medical humanities are an interdisciplinary field that combines the humanities, social sciences, and arts with medical education and practice. It fosters a multidisciplinary understanding of the human condition, patient suffering, the roles of ...
SeyedAmir Mohseni, Siavash Moradi, Fattane Amuei   +2 more
doaj   +1 more source

Construction of the Medical and Health Humanities System in China

Yixue yu zhexue
During the advancement of the Healthy China initiative, facing the needs of social development and public health in the new era, the construction of a medical and health humanities system has become increasingly important and urgent.
Zhiguang DUAN, Chen WANG, Yan SHI
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Taking medical humanities forward [PDF]

Journal of Educational Evaluation for Health Professions, 2011
P. Ravi Shankar, Rano M Piryani
doaj   +1 more source

Medical Humanities Today at The Ohio State University [PDF]

, 2017
2017 Annual James V. Warren Memorial Lecture, “Medical Humanities Today at The Ohio State University,” a panel discussion moderated by Linda Stone, MD, The Ohio State University College of Medicine, featuring faculty from The Ohio State University Center
Lawrence, Susan, Phelan, James, 1951-, Hawkins, Julia Nelson, Habash, Diane, Brown, Elinor   +4 more
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