Results 121 to 130 of about 401,158 (318)

Interdisciplinary and cultural perspective on the internationalization of Higher Education: a focus on East Asia [PDF]

, 2014
Recent studies have shown that the meaning of internationalization, the means to implement it and the extent of internationalization policies depend much on specific subject matter.
Yang, R
core  

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Art and the Human Condition: Incorporating Visual Analysis of Artworks into a Undergraduate Pre-Medicine Curriculum [PDF]

, 2012
This thesis project presents a sample class session for the course, The Human Condition: An Arts Perpective (ARTH 361), which will be a part of the optional Medical Humanities minor for the pre-medicine students at Virginia Commonwealth University (VCU)
Fuqua, Elizabeth
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Construction of the Medical and Health Humanities System in China

Yixue yu zhexue
During the advancement of the Healthy China initiative, facing the needs of social development and public health in the new era, the construction of a medical and health humanities system has become increasingly important and urgent.
Zhiguang DUAN, Chen WANG, Yan SHI
doaj   +1 more source

The past, present, and future of medical humanities [PDF]

, 2017
Jane Macnaughton
openalex   +1 more source

UCL DAF (Data Audit Framework) Pilot: final report [PDF]

, 2009
The UCL DAF (Data Audit Framework) pilot implementation project was funded by JISC for a period of seven months (August 2008-March 2009) to trial the implementation of the DAF methodology at ...
Polydoratou, P.
core  

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source