Results 121 to 130 of about 56,083 (277)
Molecular Oncology, Volume 19, Issue 10, Page 2978-2988, October 2025.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source
Does medical humanities matter? The challenge of COVID-19. [PDF]
Med Humanit, 2023 Macnaughton J.
europepmc +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
Medical Humanities: time to join the mainstream of medical education
MedEdPublish, 2018 Medical Humanities has grown in stature and scholarship in recent years. Much of the credit for this must go to academic humanists. Medical academics, with some notable exceptions, have not taken ownership of the discipline. The time has come for this to
Muiris Houston
doaj
Postdigital health practices: new directions in medical humanities. [PDF]
Med Humanit, 2023 Pietrzak-Franger M.
europepmc +1 more source
Nemesis, Sisyphus, and a contribution from the medical humanities to health research [PDF]
, 2003 R. H. T. Edwards
openalex +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Molecular Oncology, Volume 19, Issue 10, Page 2797-2821, October 2025.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach +8 more
wiley +1 more source
Analyzing the Perspectives of Instructors of General Medical Modules on the Inclusion of Health Humanities Fundamentals in the Curriculum [PDF]
Journal of Mazandaran University of Medical SciencesBackground and purpose: Medical/Health Humanities is considered a new field of study. This concept is looking for an answer to the question of how to make medical education, medical processes, and practice more humane so that the human aspects are ...
SeyedAmir Mohseni +2 more
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