Results 181 to 190 of about 6,044,633 (290)

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

In love with medical humanities! A survey on medical students' opinions and satisfaction with an integrated elective course. [PDF]

BMC Med Educ
Tusoni F, Ferrara V, Franceschini A, Cofini V, Giusti L, Iagnemma A, Romano S, Necozione S, Fabiani L.   +8 more
europepmc   +1 more source

Narrative medicine as a roadmap to medical humanities in dental education. [PDF]

J Dent Sci, 2023
Chen YT, Yu CH, Chang YC.
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Integrating medical humanities in undergraduate medical education: a curricular model aligned with the InspirE5 framework. [PDF]

BMC Med Educ
Coronado-Vázquez V, Monge Martín D, Arrimadas Salinas S, Carr S, Caballero Martínez F, Álvarez Montero S.   +5 more
europepmc   +1 more source

The quantified analysis of the correlation between medical humanities curriculums and medical students' performance. [PDF]

BMC Med Educ, 2023
Huang SS, Ho CC, Chu YR, Wu JW, Yang YY.
europepmc   +1 more source

French Studies and Medical Humanities: Critical Intersections

This book articulates the specific affinity between French and Francophone Studies and the burgeoning field of Medical Humanities, grounded in the history of medicine in France, in the particularity of French Republican Universalism, and in the French ...

core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Disruption, transformation and silos: medical humanities and the management gurus. [PDF]

Med Humanit
Miller G.
europepmc   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source