Results 181 to 190 of about 404,041 (294)

Integrating medical humanities in undergraduate medical education: a curricular model aligned with the InspirE5 framework. [PDF]

open access: yesBMC Med Educ
Coronado-Vázquez V   +5 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

The Emotional Anatomy of Diagnosis: A Medical Humanities Approach to Empathy in Pathology. [PDF]

open access: yesDiagnostics (Basel)
Cocuz IG   +10 more
europepmc   +1 more source

A Pilot Study to Understand the Role of Medical Humanities in Medical Education. [PDF]

open access: yesMed Sci Educ, 2022
Pitcher C   +5 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Perception of Medical Humanities among Polish Medical Students: Qualitative Analysis. [PDF]

open access: yesInt J Environ Res Public Health, 2022
Makowska M   +4 more
europepmc   +1 more source

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