Results 61 to 70 of about 56,083 (277)

Comparison of Chinese and foreign medical humanities teaching methods [PDF]

open access: yesJichu yixue yu linchuang, 2020
With the advance of medical education reform, the teaching methods of medical humanities courses in the international arena are constantly innovating and remodeling.
GUO Xu-fang, LIU Jun-xiang, LIU Hui, HE Zhong
doaj  

Serial amplification of tau filaments using Alzheimer's brain homogenates and C322A or C322S recombinant tau

open access: yesFEBS Letters, EarlyView.
We investigated the seeded assembly of 0N3R tau and two variants, C322A and C322S, designed to model the mutation landscape at residue 322, using Alzheimer's disease brain homogenates in a real‐time quaking‐induced conversion (RT‐QuIC) assay. The C322A variant formed filaments that partially resembled the paired helical filament (PHF) structure ...
Alessia Santambrogio   +9 more
wiley   +1 more source

Medical humanities in practice [PDF]

open access: yesBMJ, 2017
Stephanie Matthews and colleagues look at why you might want to go to a medical humanities ...
Matthews, Stephanie   +3 more
openaire   +2 more sources

ACSS2 involved in acetyl‐CoA synthesis regulates skeletal muscle function

open access: yesFEBS Letters, EarlyView.
The enzyme acyl‐coenzyme A synthetase short‐chain family member‐2 (ACSS2) catalyzes the conversion of acetate to acetyl‐CoA, but its function in skeletal muscle is unclear. We studied ACSS2 deficiency in mouse and fly models. Skeletal muscle from the mouse model showed atrophic fibers, excess lipid, and depleted NADH.
Mekala Gunasekaran   +6 more
wiley   +1 more source

Medical humanities and philosophy of medicine [PDF]

open access: yesMedicine, Health Care and Philosophy, 2007
Over the past 30 years — starting in the United States — an interest in ‘medical humanities’ has emerged. In the same period modern ‘philosophy of medicine’ developed. Although the medical humanities are sometimes presented under the flag of medical philosophy, there are good reasons to consider these fields separately.
Dekkers, W.J.M., Gordijn, B.
openaire   +4 more sources

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

open access: yesFEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican   +7 more
wiley   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

open access: yesFEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil   +5 more
wiley   +1 more source

Do the medical humanities enrich learning during an undergraduate anaesthetic placement?

open access: yesMedEdPublish, 2018
The value of humanities may not be immediately apparent to those focused on the medical sciences. Medical humanities offer a range of learning opportunities, complementing the sciences to enhance medical education (Lake, Jackson and Hardman, 2015 ...
Helen Westall, Amardeep Riyat
doaj  

Humanities for medical students? A qualitative study of a medical humanities curriculum in a medical school program

open access: yesBMC Medical Education, 2006
Background Today, there is a trend towards establishing the medical humanities as a component of medical education. However, medical humanities programs that exist within the context of a medical school can be problematic.
Troein Margareta   +2 more
doaj   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

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