Results 71 to 80 of about 72,882 (281)

Clinical Ethics in the Context of Medical Humanities

open access: yes, 2022
Medical humanities are vital for increasing clinical effectiveness. There is a crisis in medicine and bioethics as the epistemological status of medicine has been challenged and the goals of healthcare are often in tension.
Picozzi M., Nicoli F.
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Medical Humanities in Teaching

open access: yes, 2020
There is a wealth of different ways of putting Medical Humanities into teaching. This diversity shows the fecundity and cross-fertilization of Medical Humanities as an inter-disciplinary and critical academic field reflecting the widely varied Medical ...
Guido Furci
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Suggestions for the Improvement of Medical Humanities Education

open access: yes, 2010
Medical humanities has become a third area of medical education following basic and clinical medicine. Also, in the national evaluation of medical schools, medical humanities education is an important factor.
연세대학교 의과대학
core  

The Humanities as Medical Equipment [PDF]

open access: yes, 2018
2018 Annual James V. Warren Memorial Lecture featuring Tod S. Chambers, PhD, Associate Professor, Northwestern Feinberg School of Medicine, "The Humanities as Medical Equipment," Thursday, April 12, 2018, James Hospital Conference Center, The Wexner ...
Chambers, Tod S.
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Research on the Medical Humanities Education Curriculum Setting and Evaluation Systems in the United States, the United Kingdom, Germany, and Japan

open access: yesYixue yu zhexue
By using historical and logical methods, this study summarizes the representative medical humanities curriculum settings and evaluation systems of higher education institutions in the United States, the United Kingdom, Germany, and Japan.
Yuan JI, Huixian CUI
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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