Results 131 to 140 of about 13,929,601 (291)

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Humanities in medical education

International Journal of Applied and Basic Medical Research, 2020
openaire   +2 more sources

Faculty development to support medical humanities in medical education – Pilot results and insights

Introduction: Through collaborative pedagogical initiatives, the medical humanities (MH) have the potential to support healthcare professionals in developing various competencies in medical education (ME).
Filomar Cortezano Tariao, Lalit Kumar Radha Krishna, Eng-Koon Ong, Yingxuan Chen, Min Chiam, Faith Ng, Wen-Shan Sim, Jamie Zhou, April Thant Aung, Tariao, Filomar Cortezano, Krishna, Lalit Kumar Radha, Aung, April Thant, Zhou, Jamie, Chen, Yingxuan, Sim, Wen-Shan, Chiam, Min, Ong, Eng-Koon, Ng, Faith   +17 more
core   +1 more source

To examine the associations between medical students’ conceptions of learning, strategies to learning, and learning outcome in a medical humanities course

, 2020
[[abstract]]Background By learning medical humanities, medical students are expected to shift from handling the diseases only to seeing a whole sick person.
Chiu, Yu-Chun;Chiu, Yu-Chun;Li, Jyh-Chong;Liang, Jyh-Chong;Hs, Hong-Yuan;Hsu, Hong-Yuan;Tzong-Shinn;Chu, Tzong-Shinn;林冠含;Lin, Kuan-Han;Che, Yen-Yuan;Chen, Yen-Yuan;Chin-Chung, T;Tsai, Chin-Chung
core  

Medical Humanities: To Cure Sometimes, To Relieve Often, To Comfort Always

, 2005
The medical humanities are concerned with “the science of the human”, and bring the perspectives of disciplines such as history, philosophy, literature, art and music to understanding health, illness and medicine.
Gordon, Jill
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Teaching Portfolios in Medical Education [PDF]

, 2009
The purpose of the study was to investigate the concept and content of teaching portfolios and to consider the use of teaching portfolios in medical education.
연세대학교 의과대학
core  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Competency-Based Medical Education: Possibilities and Limitations [PDF]

, 2011
Competency and competency-based education are topics of great interest to educators and administrators at most stages of undergraduate and postgraduate medical training.
연세대학교 의과대학
core  

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source