Results 31 to 40 of about 4,299,186 (232)
ABSTRACT Objective Spinocerebellar ataxias (SCAs) are a group of genetically heterogeneous neurodegenerative diseases causing progressive deterioration and reduced quality of life. Therapeutic advances have been limited by a lack of sensitive anatomic, functional, or diffusion imaging‐based biomarkers.
David J. Arpin+11 more
wiley +1 more source
The topic for this paper is an overview of medical informatics in the United States, what it is, how it is used in patient care, and what role librarians play in it.
Becker, Marie E.
core
ABSTRACT Objective To estimate the risk of epilepsy associated with stroke in a community‐based cohort, with consideration of stroke type, number, and severity. Methods Data from 15,100 Atherosclerosis Risk in Communities (ARIC) Study participants without stroke at baseline (1987–1989) were analyzed through 12/31/2022.
Jiping Zhou+11 more
wiley +1 more source
Background In complex diseases, it is challenging to assess a patient's disease state, trajectory, treatment exposures, and risk of multiple outcomes simultaneously, efficiently and at the point of care. Methods We developed an interactive patient‐level data visualization and analysis tool (VAT) that automates illustration of a scleroderma patient's ...
Ji Soo Kim+18 more
wiley +1 more source
Hydroxychloroquine Associated with Lower Glomerular Filtration Rate Decline in Lupus Nephritis
Background Hydroxychloroquine (HCQ) protects kidney function in lupus nephritis (LN) by preventing flares, yet some cohort studies show no significant benefit in kidney function with HCQ. Clarifying these conflicting findings by showing early and long‐term benefits of HCQ on kidney function preservation is critical. Therefore, we analyzed data from our
Shivani Garg+9 more
wiley +1 more source
Chronic Opioids in Gout: A Matched Cohort Study from the Veteran's Health Administration
Objective Though used frequently to treat flare, risk of chronic opioid exposure in gout has not been well defined. In this study, we examined the hypothesis that people with gout are more likely than individuals without gout to be prescribed chronic opioids over time.
Lindsay N. Helget+7 more
wiley +1 more source
Systematic Review of Medical Informatics–Supported Medication Decision Making
This systematic review sought to assess the applications and implications of current medical informatics–based decision support systems related to medication prescribing and use.
B. Melton
semanticscholar +1 more source
Advancing Medical Imaging Informatics by Deep Learning-Based Domain Adaptation
Summary Introduction: There has been a rapid development of deep learning (DL) models for medical imaging. However, DL requires a large labeled dataset for training the models.
A. Choudhary+3 more
semanticscholar +1 more source
Activation of NF‐κB Signaling by Optogenetic Clustering of IKKα and β
This study presents an optogenetic approach for graded clustering of eGFP‐fused proteins using an eGFP‐specific nanobody and engineered Cryptochrome 2 variants. The method enables potent, reversible activation of NF‐κB signaling via endogenous pathways, as confirmed by RNA sequencing. This versatile system provides a spatially and temporally controlled
Alexandra Anna Maria Fischer+8 more
wiley +1 more source
Medical Informatics Education - Past, Today and Future
The development of medical informatics goes back to the second half of the twentieth century with the start of the automation of processes. Medical informatics education plays an important role in the education of health care providers and medical ...
I. Masic, P. Haris, Za
semanticscholar +1 more source