Results 91 to 100 of about 4,513,419 (307)

System hazards in managing laboratory test requests and results in primary care: medical protection database analysis and conceptual model [PDF]

, 2015
Objectives To analyse a medical protection organisation's database to identify hazards related to general practice systems for ordering laboratory tests, managing test results and communicating test result outcomes to patients.
Bowie, Paul, Dinwoodie, Mark, Hepworth, Neil, McKay, John, Price, Julie   +4 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

A comprehensive review of Proficiency Testing / Interlaboratory Comparisons Policies of the EA-MLA signatories applicable to medical laboratories

Romanian Journal of Laboratory Medicine
Proficiency Testing/Interlaboratory Comparisons play an important role that is widely accepted in demonstrating the validity of results of any laboratory and inspection body.
Ilinca Radu, Luțescu Dan Adrian, Sfeatcu Ruxandra Ionela, Gherlan Iulian, Dănciulescu-Miulescu Rucsandra-Elena, Țâncu Ana Maria Cristina   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Implementation of Quality Management System in Iranian Medical Laboratories [PDF]

Iranian Journal of Public Health, 2009
Reference health Laboratory of Iran (RHL) has been established under the Secretary of Health in 2007. This organization has been developed from integration of Reference laboratories of Iran, Directorate of General Affairs and Laboratory de­partment of ...
P Dahim , N Safadel , F Rashed Marandi, K Khodaverdian, M Rahnamaye Farzami   +4 more
doaj   +1 more source

Economic consequences of near-patient test results - the case of tests for the Helicobacter Pylori bacterium in dyspepsia [PDF]

Diagnostic tests and in particular laboratory tests are often important in diagnostic work-up and monitoring of patients. Therefore the economic consequences of medical actions based on test results may amount to a substantial proportion of health ...
Fauli, Siri, Thue, Geir
core  

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Parasitic Contamination of Consumed Vegetables in Golestan Province, 2012

Medical Laboratory Journal, 2014
Background and Objective: Nowadays, effective human resources management plays an important role in success of organizations. In order to achieve high efficiency of limited resources, managers of organizations try to allocate the best possible human ...
A Kazemi, K Esmaili Torkanpouri
doaj