Results 101 to 110 of about 4,513,419 (307)

Blood Sample Collection Errors in Medical Laboratories

Journal of Preventive, Diagnostic and Treatment Strategies in Medicine
BACKGROUND: The majority of preanalytical errors that arise during the preanalytical process are mostly due to the absence of established sample collection procedures, which include patient preparation and conditioning according to the required analysis ...
Ali M. A. Al-Kufaishi, Noor J. T. Al-Musawi   +1 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Safety management of medical neurobiology laboratory [PDF]

Jichu yixue yu linchuang, 2020
More and more attention has been paid to the safety of laboratory in colleges. The laboratory biosafety management system following the principle of human safety is the pre-condition of a routine laboratory operation.Under the national regulation and ...
HAN Wen-juan, LUO Ceng, XIE Rou-gang, WANG Wen-ting, WU Sheng-xi
doaj  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Skylab mobile laboratory [PDF]

The Skylab mobile laboratory was designed to provide the capability to obtain necessary data on the Skylab crewmen 30 days before lift-off, within 1 hour after recovery, and until preflight physiological baselines were reattained.
Larue, M. A., Primeaux, G. R.
core   +1 more source

Exploring unlikely errors using video games: An example in number entry research [PDF]

, 2012
A common and important feature of many safety critical interactive devices is number entry. In hospitals, number entry takes the form of setting drug parameters such as doses, volumes, etc. There are several ways a number entry interface can be designed -
Cox, Anna, Curzon, Paul, Iacovides, Ioanna, Oladimeji, Patrick, Thimbleby, Harold   +4 more
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

The application and challenges of ChatGPT in laboratory medicine

Advances in Laboratory Medicine
In recent years, with the rapid development of artificial intelligence technology, chatbots have demonstrated significant potential in the medical field, particularly in medical laboratories.
Niu Zhili, Kuang Xiandong, Chen Juanjuan, Cai Xin, Zhang Pingan   +4 more
doaj   +1 more source

Medical Laboratory Staff Awareness’ Concerning Occupational Health Hazards in Public Hospitals

Kufa Journal for Nursing Sciences
Background :Medical Laboratory staff are exposed to a wide range of hazards associated with the materials they employ and the methods they use in their work.
Hayder Nidhal Kamil, Mansour Abdullah Falah   +1 more
doaj   +1 more source