Results 111 to 120 of about 4,513,419 (307)
Baron Guillaume Dupuytren: when brilliance combats professionalism. [PDF]
, 2012 Baron Guilluame Dupuytren was a French anatomist and surgeon who practiced during the 1800s and is considered by some to be the most brilliant and gifted surgeons of his time.
Devitt, MD, Sean M. +2 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Payesh, 2017 Objective (s): Equity in distribution of health services is one of the goals of health policy makers. Thus, an study entitled “modeling geographical access to medical laboratory services in Iran” was conducted in 2014. The present article is a case study
Jila Sadighi +10 more
doaj
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Salāmat-i kār-i Īrān, 2016 Background and aims: Musculoskeletal disorders are the most prevalent occupational injuries and disability in the world. One of the most important risk factors of these disorders is awkward posture.
S Falaki +4 more
doaj
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Geographical accessibility to medical laboratory services in Iran: Takab case study
Payesh, 2015 Objective (s): One of the most important strategies to achieve equity is facilitating population access to health services. As such geographical accessibility modeling was suggested.
Jila Sadighi +9 more
doaj
Accreditation of Medical Laboratories in Croatia – Experiences of the Institute of Clinical Chemistry, University Hospital »Merkur«, Zagreb [PDF]
, 2010 Since 2003 when the international norm for implementation of quality management in medical laboratories (EN ISO 15189, Medical laboratories – Particular requirements for quality and competence) was established and accepted, accreditation has become ...
Aida Nazor +9 more
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source