Results 51 to 60 of about 10,881,142 (301)

Cyberattack on the National Health Laboratory Service of South Africa – implications, response and recommendations

South African Medical Journal
Cybersecurity is now an integral consideration in the management of healthcare institutions in this modern technological era. Cyberattacks primarily targeting healthcare institutions have increased exponentially. Recently, the information technology
S Cassim, Z C Chapanduka
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Guidelines of the German Medical Association on quality assurance in medical laboratory testing

, 2015
The Richtlinie der Bundesärztekammer zur Qualitätssicherung laboratoriumsmedizinischer Untersuchungen (Guideline of the German Medical Association on Quality Assurance in Medical Laboratory Examinations - Rili-BAEK) has been completed and published in a ...
Instand e.V., Bundesärztekammer (German Medical Association)   +1 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Application of Social Constructivism in Medical Education [PDF]

, 2020
The purpose of this study is to discuss the main principles and concepts of social constructivism, examine the literature on the application of social constructivism in medical education, and explore the meaning and limitations of the utilization of ...
Korean Medical Education Review (의학교육논단)
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Towards appropriate training for Moroccan laboratory professionals: Identifying QMS needs

Romanian Journal of Laboratory Medicine
Professional development plays a key role in improving laboratory quality management by enhancing staff skills and knowledge to implement and maintain the quality management system (QMS).
Feniche Mohammed El, Gazzaz Hassane, Omari Hajar El, El-Mouhdi Karima, Arai Mounir, Aatik Yassine El, Ouardi Abdelghani El, Kharrazi Anass, Kaddouri Ahmed Chbihi, Bouaiti El Arbi   +9 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Proceedings of the Uganda Medical Laboratory Technology Association (UMLTA)

, 2010
s of papers presentedTHE 28TH UMLTA & 5th FEAMLS SCIENTIFIC CONFERENCE THEME: “STRENGTHENING MEDICAL LABORATORY DELIVERY SYSTEM, -A GATEWAY TO ACHIEVING MILLENIUM DEVELOPMENT GOALS” Date: 18th - 19th November 2010 Venue: Churchill Courts Hotel ...
Uganda Medical Laboratory Technology Association, Federation of East African Association of Medical Laboratory Scientists   +1 more
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source