Results 91 to 100 of about 3,008,227 (355)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Immunoglobulin G2 Antibody as a Potential Target for COVID-19 Vaccine

ImmunoTargets and Therapy, 2020
Henok Andualem,1 Mulugeta Kiros,2 Sisay Getu,3 Wasihun Hailemichael1 1Immunology and Molecular Biology, Department of Medical Laboratory Science, College of Health Science, Debre Tabor University, Debre Tabor, Ethiopia; 2Medical Microbiology, Department ...
Andualem H, Kiros M, Getu S, Hailemichael W   +3 more
doaj  

Enhancing quality healthcare in Nigeria through medical laboratory services: A review

Medicine
This article explores the pivotal role of medical laboratory services in enhancing the quality of healthcare in Nigeria. Medical laboratory science is a comprehensive field that involves a diverse array of diagnostic and analytical procedures.
Abdulrahman Abdulbasit Opeyemi, E. Obeagu, Abdulwasiu O Hassan   +2 more
semanticscholar   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Novel Insight of Transcription Factor PtrA on Pathogenicity and Carbapenems Resistance in Pseudomonas aeruginosa

Infection and Drug Resistance, 2022
Ying Zhang,1,* Lingbo Wang,1,* Liqiong Chen,2 Peiwu Zhu,1 Na Huang,1 Tao Chen,1 Lijiang Chen,1 Zhongyong Wang,1 Wenli Liao,1 Jianming Cao,2 Tieli Zhou1 1Department of Clinical Laboratory, The First Affiliated Hospital of Wenzhou Medical ...
Zhang Y, Wang L, Chen L, Zhu P, Huang N, Chen T, Chen L, Wang Z, Liao W, Cao J, Zhou T   +10 more
doaj  

Occupation Profile: Medical/Clinical Lab Technologists, October 9, 2017 [PDF]

, 2017
Perform complex medical laboratory tests for diagnosis, treatment, and prevention of disease. May train or supervise staff.

core  

'Saving the lives of our dogs': the development of canine distemper vaccine in interwar Britain [PDF]

, 2013
This paper examines the successful campaign in Britain to develop canine distemper vaccine between 1922 and 1933. The campaign mobilized disparate groups around the com- mon cause of using modern science to save the nation’s dogs from a deadly disease ...
Alter, Austoker, Bedson, Berry, Blancou, Bliss, Boddie, Bradley, Bresalier, Cameron, Carr, Chick, Church, Comerford, Dalling, Dalling, Dalling, Dalling, Dalling, Dalling, Dalling, Dalling, Dalling, Edgerton, Edgerton, Edgerton, Eichhorn, Fleming, Fletcher, Gardiner, Greenwood, Griffin, Harding, Harris, Hobday, Hobday, Horsley, Hunter, Hunting, Jones, Kohler, Laidlaw, Laidlaw, Laidlaw, Lawrence, Lawrence, McBride, MICHAEL BRESALIER, MICHAEL WORBOYS, O'Brien, Pattison, Phisalix, Sturdy, Sweet, Thomson, Thomson, Topley, Waddington, Woods   +58 more
core   +2 more sources

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Work-related musculoskeletal problems related to laboratory training in university medical science students: a cross sectional survey

BMC Public Health, 2018
Background Work-related musculoskeletal problems impact everyday function, working ability, and quality of life. Unaddressed musculoskeletal problems can lead to major injury and loss of function, contributing to participation restrictions, economic loss
Stefania Penkala, Hannan El-Debal, Kristy Coxon   +2 more
doaj   +1 more source