Results 101 to 110 of about 36,733,388 (297)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Evaluating the Applicability of Advanced Large Language Models in Laboratory Medicine Test Questions: A Comparative Performance Study

Advances in Medical Education and Practice
Wenzheng Han,1,* Wenkai Zhu,1,* Gang Feng,1,* Yankang Wang,1 Guang Chen,2 Huan Zhou,3 Bin Quan,4 Qiwen Wu,1 Jianghua Yang,4 Kai Jin,5 Shaoneng Tao,6 Xiaoning Li,1 Qing Chen6 1Department of Clinical Laboratory, The First Affiliated
Han W, Zhu W, Feng G, Wang Y, Chen G, Zhou H, Quan B, Wu Q, Yang J, Jin K, Tao S, Li X, Chen Q   +12 more
doaj  

Helicobacter pylori Pathogenicity Islands and Giardia lamblia Cysteine Proteases in Role of Coinfection and Pathogenesis

Infection and Drug Resistance, 2022
Mihret Tilahun,1 Alemu Gedefie,1 Chernet Belayhun,2 Zenawork Sahle,3 Admasu Abera3 1Department of Medical Laboratory Sciences, College of Medicine and Health Science, Wollo University, Dessie, Ethiopia; 2Department of Medical Laboratory Science, Mehal ...
Tilahun M, Gedefie A, Belayhun C, Sahle Z, Abera A   +4 more
doaj  

Laboratories Medical Bioinformatics set up at Medical Sciences University

مجله ایرانی آموزش در علوم پزشکی, 2017
Laboratories Medical Bioinformatics set up at Medical Sciences ...
Sorayya Ghasemi, Shahram Tahmasebian
openaire   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

More Than Half Prevalence of Protozoan Parasitic Infections Among Diarrheic Outpatients in Eastern Tigrai, Ethiopia, 2019; A Cross-Sectional Study

Infection and Drug Resistance, 2020
Brhane Berhe,1 Fitsum Mardu,1 Kebede Tesfay,1 Haftom Legese,2 Gebre Adhanom,2 Hagos Haileslasie,3 Gebremedhin Gebremichail,3 Brhane Tesfanchal,4 Niguse Shishay,5 Hadush Negash2 1Unite of Medical Parasitology and Entomology, Department of Medical ...
Berhe B, Mardu F, Tesfay K, Legese H, Adhanom G, Haileslasie H, Gebremichail G, Tesfanchal B, Shishay N, Negash H   +9 more
doaj  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Medical Laboratory Director Competencies: State of the Basic Medical Sciences and Global Perspective

پیاورد سلامت, 2017
Background and Aim: There has been a long-lasting debate among medical laboratory-associated specialists about required competencies and educational background to qualify for directing medical laboratories in Iran.
Mohammad Erfan Zare, Reza Meshkani, Mojtaba Abbasi, Farhad Shaveisi Zadeh, Atefeh Nasir Kansestani   +4 more
doaj  

High Magnitude of Fecal Carriage of Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae at Debre Berhan Comprehensive Specialized Hospital, Ethiopia

Infection and Drug Resistance, 2022
Demissew Shenkute,1 Melese Hailu Legese,2 Berhanu Yitayew,1 Asaye Mitiku,3 Getabalew Engidaye,4 Saba Gebremichael,5 Daniel Asrat,6 Yimtubezinash Woldeamanuel6 1Department of Medical Laboratory Science, College of Health Sciences, Debre Berhan University,
Shenkute D, Legese MH, Yitayew B, Mitiku A, Engidaye G, Gebremichael S, Asrat D, Woldeamanuel Y   +7 more
doaj  

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source