Results 101 to 110 of about 1,403,791 (257)

Laboratories Medical Bioinformatics set up at Medical Sciences University

open access: yesمجله ایرانی آموزش در علوم پزشکی, 2017
Laboratories Medical Bioinformatics set up at Medical Sciences ...
Sorayya Ghasemi, Shahram Tahmasebian
openaire   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Medical Laboratory Director Competencies: State of the Basic Medical Sciences and Global Perspective

open access: yesپیاورد سلامت, 2017
Background and Aim: There has been a long-lasting debate among medical laboratory-associated specialists about required competencies and educational background to qualify for directing medical laboratories in Iran.
Mohammad Erfan Zare   +4 more
doaj  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Bacterial Profile and ESBL Screening of Urinary Tract Infection Among Asymptomatic and Symptomatic Pregnant Women Attending Antenatal Care of Northeastern Ethiopia Region [Corrigendum]

open access: yesInfection and Drug Resistance, 2020
Belete MA. Infect Drug Resist. 2020;13:2579–2592. The author has advised the affiliation list on page 2579 is incorrect. The correct author list and affiliations are as follows.Melaku Ashagrie Belete1,2Dawit Gebreegziabiher2Letemichael ...
Belete MA
doaj  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Comparing the Immunology Learning Environment in International Medical Campus of Qeshm, Paramedical and Dental Schools of Hormozgan University of Medical Sciences

open access: yesDevelopment Strategies in Medical Education, 2014
Introduction: Immunology Department of Hormozgan University of Medical Sciences is responsible for teaching immunology in all affiliated medical colleges in Hormozgan province.
Behjat Naserian   +3 more
doaj  

TRIM55 Promotes Proliferation of Hepatocellular Carcinoma Through Stabilizing TRIP6 to Activate Wnt/β-Catenin Signaling

open access: yesJournal of Hepatocellular Carcinoma, 2023
Xun Lu,1– 3 Yue Yuan,4 Ning Cai,1– 3 Dean Rao,1– 3 Min Chen,4 Xiaoping Chen,1– 3 Bixiang Zhang,1– 3 Huifang Liang,1– 3 Lei Zhang3,5 1Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan ...
Lu X   +8 more
doaj  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

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