FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Dual-tracer PET/CT imaging with <sup>68</sup>Ga-DOTATATE and Al<sup>18</sup>F-NOTA-FAPI for dynamic evaluation of myocardial inflammation and fibrosis in antimitochondrial antibody-positive myositis. [PDF]
Rheumatol Immunol ResQian J +5 more
europepmc +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Impact of butorphanol combined with propofol general anesthesia on laboratory indicators and reproductive outcomes in elderly patients undergoing oocyte retrieval. [PDF]
Medicine (Baltimore)Rao J +8 more
europepmc +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Elin L Wolfe, A Clifford Barger and Saul Benison, Walter B. Cannon. Volume 2: Science and society, Boston Medical Library in the Francis A Countway Library of Medicine, 2000, pp. x, 644, illus., £19.95 (hardback 0-674-00251-2). Distributed by Harvard University Press. [PDF]
, 2002 Lawrence, CJ
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Malaria parasitemia and its association with liver function parameters, and lipid profile among malaria-infected adult patients in western Ethiopia: A comparative cross-sectional study. [PDF]
PLoS OneCheckole N +8 more
europepmc +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Corrigendum to "Metabolic modulation of TCA cycle by S-nitrosylation in <i>Monascus</i> spp." [Synthetic and Systems Biotechnol 12 (2026) 490-501]. [PDF]
Synth Syst BiotechnolMeng Z, Tan Y, Duan Y, Li M.
europepmc +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source