Results 241 to 250 of about 2,474,653 (302)

Getting down to the Business of Science: How Undergraduate Research Derailed my Career Plan and put me on a Path to Professional Success [PDF]

, 2012
Mantis, Nicholas J.
core   +1 more source

Allosteric activation mechanism of the type VII CRISPR-Cas system. [PDF]

Nucleic Acids Res
Zhang S, Liu Y, Wu W, Liu Z, He Q, Wang T, Yang J, Yin H, Yuan Z, Zhang H.   +9 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Planning for the future of the American Society for Microbiology's Health Unit by the Council on Microbial Sciences. [PDF]

mSphere
Fox AJ, Prinzi AM, Wamburu NW, Moore NM, Lieberman MM, Shier K, Haigwood NL.   +6 more
europepmc   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Benchmarking large language models for medical education: performance on the clinical laboratory technician qualification examination. [PDF]

Front Med (Lausanne)
Wang Y, Jiang Y, Jin W, Lin W, Xu Y, Wang J, Wang X, Fang Z.   +7 more
europepmc   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Distinct Effects of Nonselective Rho-Kinase Inhibitor Fasudil and Selective Rho-Kinase 2 Inhibitor KD025 on Serotonin and Dopamine Release in the Nucleus Accumbens of Mice. [PDF]

Neuropsychopharmacol Rep
Tanaka R, Zhu W, Nagai T, Nabeshima T, Kaibuchi K, Ozaki N, Ikesue H, Mizoguchi H, Yamada K.   +8 more
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Transient changes in body weight and behavior during the placentation period in non-human primates and rodents. [PDF]

Sci Rep
Yano-Nashimoto S, Shinozuka K, Kurachi T, Kagawa K, Sakamoto KQ, Shigeno Y, Niimi K, Kuroda KO, Yamaguchi S.   +8 more
europepmc   +1 more source