Results 51 to 60 of about 242,025 (294)
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
GMS Medizin – Bibliothek – Information, 2010 The focus of the current issue 3/2010 of GMS Medizin – Bibliothek – Information is the annual conference 2010 of the German Medical Libraries Association in Mainz. The motto of the conference was “all – simply – immediately: service in medical libraries”.
Bauer, Bruno
doaj
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
GMS Medizin – Bibliothek – Information, 2015 The focus of the current issue 3/2015 of GMS Medizin – Bibliothek – Information is the annual conference 2015 of the German Medical Libraries Association in Mannheim. The motto of the conference was “Libraries in progress”. The authors in this issue are
Bauer, Bruno
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The Interdisciplinary Academic Library: A Medical Humanities Case Study [PDF]
, 2021 Kathleen Kasten-Mutkus, Jamie Saragossi
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Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Forum Bibliotek Medycznych, 2020 The collections of the Main Library of the Medical University of Gdańsk both chronologically and in terms of content go beyond the University’s existence and exceed the area of medical topics.
Małgorzata Florianowicz +2 more
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Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
An Examination of the Factors Affecting the Adoption of Digital Transformation by Librarians at Medical Universities Based on Rogers' Diffusion of Innovation Theory [PDF]
Taṣvīr-i salāmatBackground. Digital transformation refers to the changes resulting from the implementation of digital technologies across all aspects of human life. This study aims to explore the factors affecting the adoption of digital transformation by librarians at ...
Mohammadreza Azadifar +3 more
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Journal of the American Medical Association, 1909 One of the serious problems which confronts the management of every library is the proper and equable apportioning of the book fund to the several departments. The problem is, of necessity, a flexible one and varies with the environment, the resources and the policy of the individual library.
openaire +1 more source