Results 81 to 90 of about 676,265 (337)

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Presente y futuro de los servicios de las bibliotecas médicas. Revisión de la literatura y estudio realizado en un hospital de más de 1.400 camas

Revista Española de Documentación Científica, 2006
En los últimos años se han producido grandes cambios en la forma de acceder a la información en medicina y esto ha incidido profundamente en las bibliotecas médicas y en el modo de organizar sus servicios.
M. Rodríguez del Castillo Martín, M. M. Rodríguez del Águila, C. Herrera Espiñeira, A. Quero Rufián, C. Martínez Cirre, F. Lechuga Rodríguez del Castillo   +5 more
doaj   +1 more source

The New Knowledge Environment: Quality Initiatives in Health Sciences Libraries [PDF]

, 1996
published or submitted for ...
Nagle, Ellen
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

AGMB-Arbeitskreis österreichischer Medizinbibliothekarinnen und -bibliothekare (AGMB.AT): Bericht vom 8. Treffen 2018 und vom 9. Treffen 2019

GMS Medizin – Bibliothek – Information, 2019
The work group Austrian Medical Librarians (AGMB.AT) is a platform for the exchange of information and experience amongst medical librarians. On Dec 12, 2018 the 8 meeting took place at the Medical University Vienna.
Bauer, Bruno, Dollfuß, Helmut, Frank, David   +2 more
doaj   +1 more source

Special Libraries, September 1966 [PDF]

, 1966
Volume 57, Issue 7https://scholarworks.sjsu.edu/sla_sl_1966/1006/thumbnail ...
Special Libraries Association
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Progress Toward a National Serials Data System [PDF]

, 1970
published or submitted for ...
Adams, Scott
core  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source