Results 51 to 60 of about 30,768,316 (308)

Evidenzbasierte Medizin – Chance für Medizinbibliotheken

open access: yesGMS Medizin – Bibliothek – Information, 2020
The focus of the current issue 1-2/2020 of GMS MEDIZIN – BIBLIOTHEK – INFORMATION is on evidence-based medicine and systematic review in German, Austrian and Swiss medical libraries.
Buroh, Sabine   +2 more
doaj   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

Bio-Medical Library Bulletin, No. 53 (1977-09) [PDF]

open access: yes, 1977
Bio-Medical Library. (1977). Bio-Medical Library Bulletin, No. 53 (1977-09).
Bio-Medical Library
core  

Status of the Cybernetic Model Components in the Libraries of Iran's Type 1 Medical Sciences Universities [PDF]

open access: yesبازیابی دانش و نظام‌های معنایی
IntroductionCybernetics, a science that emerged in the 20th century, has rapidly grown and penetrated various disciplines. Since its inception, cybernetics has experienced significant and continuous growth, with communication and the concepts of message ...
Fereshteh Bayanlou   +2 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Der Webauftritt – eine Dauerbaustelle / The website – constantly under construction

open access: yesGMS Medizin – Bibliothek – Information, 2010
Three web projects for the site http://www.ma.uni-heidelberg.de/bibl/ of the Library of the Medical Faculty of Mannheim are shown from the webteam’s perspective – from the first brainstorming sessions to the final design: relaunch, translation, usability-
Boeckh, Dorothee
doaj  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

AGMB 2020: Innovativ in die nächsten 50 Jahre

open access: yesGMS Medizin – Bibliothek – Information, 2020
The unexpected death of the longtime editor-in-chief of this journal overshadows the current issue, which is otherwise all about the AGMB annual conference 2020. In addition to the obituary for Mr.
Dollfuß, Helmut
doaj   +1 more source

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