Results 71 to 80 of about 29,415,403 (310)
Bio-Medical Library Bulletin, No. 60 (1979-02)
Bio-Medical Library. (1979). Bio-Medical Library Bulletin, No. 60 (1979-02).
Bio-Medical Library
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Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Bio-Medical Library Bulletin, No. 78 (1983-04)
Bio-Medical Library. (1983). Bio-Medical Library Bulletin, No. 78 (1983-04).
Bio-Medical Library
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Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Medizinbibliothekarische Bibliografie 2012 [The Medical Librarian’s Bibliography 2012]
[english] The Medical Librarian’s Bibliography 2012 lists all articles from GMS Medizin – Bibliothek – Information and selected publications relevant to medical librarians from following journals: ABI Technik, Bibliothek Forschung und Praxis ...
Bauer, Bruno
doaj +1 more source
Bio-Medical Library Bulletin, No. 51 (1977-04)
Bio-Medical Library. (1977). Bio-Medical Library Bulletin, No. 51 (1977-04).
Bio-Medical Library
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This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Bio-Medical Library Bulletin, No. 112 (1993-10)
Bio-Medical Library. (1993). Bio-Medical Library Bulletin, No. 112 (1993-10).
Bio-Medical Library
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