Results 91 to 100 of about 4,078,666 (364)

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

On the Theory of Evolution Versus the Concept of Evolution: Three Observations [PDF]

, 2011
Here we address three misconceptions stated by Rice et al. in their observations of our article Paz-y-Miño and Espinosa (Evo Edu Outreach 2:655–675, 2009), published in this journal.
A Lazcano, A Lazcano, A Lazcano, AP Johnson, Avelina Espinosa, BA Bishop, C Darwin, C Zimmer, CG Paz-y-Miño, EC Scott, G Brumfield, Guillermo Paz-y-Miño C., H Follmann, J Peretó, JD Miller, JL Bada, JP Schrum, JR Downie, JW Rice, L Zaikowski, LM Krauss, LS Nadelson, R Trani, SJ Gould, SL Miller   +24 more
core   +2 more sources

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Variations in the practice of molecular radiotherapy and implementation of dosimetry: results from a European survey

EJNMMI Physics, 2017
Background Currently, the implementation of dosimetry in molecular radiotherapy (MRT) is not well investigated, and in view of the Council Directive (2013/59/Euratom), there is a need to understand the current availability of dosimetry-based MRT in ...
Katarina Sjögreen Gleisner, Emiliano Spezi, Pavel Solny, Pablo Minguez Gabina, Francesco Cicone, Caroline Stokke, Carlo Chiesa, Maria Paphiti, Boudewijn Brans, Mattias Sandström, Jill Tipping, Mark Konijnenberg, Glenn Flux   +12 more
doaj   +1 more source

Doctoral Education and Academic Research (in India) [PDF]

, 2006
[Excerpt] The state of doctoral education and academic research in India is poor and the country has scant representation among the world’s great universities. The decline has happened in spite of early achievements.
Chatterjea, Arkadev, Moulik, Satya P
core   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Effect of Traditional Aerobic Exercises Versus Sprint Interval Training on Pulmonary Function Tests In Young Sedentary Males: A Randomised Controlled Trial [PDF]

Journal of Clinical and Diagnostic Research, 2013
Background: Physical inactivity is now a global noncommunicable disease. Current recommendations from American College of Sports Medicine, American Heart Association and UK medical officers for physical activity are difficult to implement, due to time
BADAAM KHALED M., MUNIBUDDIN A., KHAN S.T., Choudhari S.P., Doiphode R.   +4 more
doaj   +1 more source

Quality Assurance in Diagnostic Medical Exposures in Ghana - A Medical Physicist’s Perspective

, 2012
It is well known that medical expsoure procedures such as diagnostic radiology, nuclear medicine and radiotherapy remains the largest source of man made exposure to ionising ra‐ diation and continues to grow substantially.
S. Inkoom
semanticscholar   +1 more source

THE MEDICAL PHYSICIST - SCIENTIST BEHIND THE CURTAIN

Journal of Medical pharmaceutical and allied sciences, 2021
Ionizing radiation has validated its existence and effectiveness in modern medicine for both diagnostic and therapeutic use. For the last decade rapid growth in medical radiation application has witnessed in India towards the betterment of mankind, for safe and quality clinical practice, radiation protection and quality assurance.
Gaurav Mishra, Bhushan N. Lakhkar, Anurag A. Luharia   +2 more
openaire   +2 more sources

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source