Results 101 to 110 of about 59,810 (337)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Single institution implementation of permanent 131Cs interstitial brachytherapy for previously irradiated patients with resectable recurrent head and neck carcinoma [PDF]

open access: yes, 2019
Purpose: Permanent interstitial brachytherapy is an appealing treatment modality for patients with locoregional recurrent, resectable head and neck carcinoma (HNC), having previously received radiation.
Bar-Ad, Voichita   +10 more
core   +1 more source

Vision to reality: From Robert R. Wilson's frontier to Leon M. Lederman's Fermilab

open access: yes, 2011
This paper examines the roles of vision and leadership in creating and directing Fermi National Accelerator Laboratory from the late 1960s through the 1980s.
Hoddeson, Lillian H., Kolb, Adrienne W.
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Six Signs of Scientism [PDF]

open access: yes, 2010
As the English word “scientism” is currently used, it is a trivial verbal truth that scientism—an inappropriately deferential attitude to science—should be avoided.
Haack, Susan
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

The accuracy of cone beam computed tomography (CBCT) technique as an image-guided radiation therapy (IGRT) technique

open access: yesJournal of the Pakistan Medical Association
Objective: To measure the setup error of the patient's positioning using cone-beam computed tomography during radiation therapy treatment fractions by finding systematic, random errors and the planned target volume errors.
Muthanna Ghadban Jwair   +5 more
doaj   +1 more source

MJM MedTalks (S01E02): A Conversation with Dr. Shirin Enger

open access: yesMcGill Journal of Medicine, 2022
Podcast Links: Spotify Anchor   McGill Journal of Medicine (MJM) MedTalks is a Podcast series where members of the McGill Faculty of Medicine and Health Sciences are interviewed on topics related to career, research, advocacy and more.
Nadia Blostein
doaj  

Friends, partners, and orphans

open access: yesMedicine Anthropology Theory, 2018
The essay juxtaposes three moments of medical infrastructure and technology aid in Phnom Penh, Cambodia: 1960, 2010, and 2005. The operative terms of these moments are relationship terms: ‘friendship’, ‘partnership’, and ‘orphan’.
Jenna Grant
doaj   +1 more source

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