Results 121 to 130 of about 59,810 (337)
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
The education of Walter Kohn and the creation of density functional theory [PDF]
, 2014 The theoretical solid-state physicist Walter Kohn was awarded one-half of the 1998 Nobel Prize in Chemistry for his mid-1960's creation of an approach to the many-particle problem in quantum mechanics called density functional theory (DFT).
Zangwill, Andrew
core
Most residency programs for radiation oncology physicists do not reflect the heightened importance of medical imaging [PDF]
, 2010 X Zhu, Rupak K. Das, Colin G. Orton
openalex +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Anticipation în the Context of Altered States of Consciousness [PDF]
, 2004 Starting from the paradigm of the material continuum we discuss the possibility to transcend the space-time reality (Here-and-Now) in the aim of investigating the energetic and informational reality, support of the continuous present.
Manolea, Aliodor
core
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
D-1 report: The first German spacelab mission [PDF]
Introduction of a new popular magazine on the DI mission, the first West German Space mission. The DI project office publishes the magazine. The German sponsored astronauts are to study the gravitational effects of reduced gravity on the human generated ...
core +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
What validation tests can be done by the clinical medical physicist while waiting for the standardization of quantitative SPECT/CT imaging? [PDF]
EJNMMI Phys, 2022 Piwowarska-Bilska H +2 more
europepmc +1 more source