Results 91 to 100 of about 59,810 (337)
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Middle East Journal of Cancer, 2014 Background: Central nervous system tumors account for 2%-5% of all malignancies in humans. These tumors account for 2% of all pediatric cancers. The worldwide incidence of primary central nervous system tumors is estimated at 3.9 (males) and 3.2 ...
Abdolazim Sedighi Pashaki +7 more
doaj
Jurnal Fisika FluxDiagnostic radiology is the most significant contributor to irradiation in the general population. Unnecessary irradiation of workers, patients, and the public during radiological procedures should be significantly reduced without affecting the medical ...
Ramacos Fardela +4 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
A nomogram to determine required seed air kerma strength in planar 131 Cesium permanent seed implant brachytherapy [PDF]
, 2019 Purpose: Intraoperatively implanted Cesium-131 ( 131 Cs) permanent seed brachytherapy is used to deliver highly localized re-irradiation in recurrent head and neck cancers.
Bar-Ad, Voichita +4 more
core +1 more source
Asking Biological Questions of Physical Systems: the Device Approach to Emergent Properties
, 2018 Life occurs in concentrated `Ringer Solutions' derived from seawater that Lesser Blum studied for most of his life. As we worked together, Lesser and I realized that the questions asked of those solutions were quite different in biology from those in the
Eisenberg, Bob
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Physics at the University of Lviv: the first two centuries in the bibliographic aspect
, 2014 A detailed bibliography related to physics at the University of Lviv (Leopolis, Lemberg, Lw\'ow) in 18th-19th centuries is presented. Over ninety works of various types are listed with a large share being illustrated by title or starting pages.
Rovenchak, Andrij
core
Getting on with the job : a response to Jones and Lockwood [PDF]
, 2008 Peter Jones and Andrew Lockwood identified some of the reasons that hospitality management research and education is in a potential spiral of decline. Undeniably one of the main reasons is that the existence of the independent Hotel School model, within ...
O'Gorman, Kevin D.
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source