Results 81 to 90 of about 58,799 (301)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Middle East Journal of Cancer, 2014 Background: Central nervous system tumors account for 2%-5% of all malignancies in humans. These tumors account for 2% of all pediatric cancers. The worldwide incidence of primary central nervous system tumors is estimated at 3.9 (males) and 3.2 ...
Abdolazim Sedighi Pashaki +7 more
doaj
Jurnal Fisika FluxDiagnostic radiology is the most significant contributor to irradiation in the general population. Unnecessary irradiation of workers, patients, and the public during radiological procedures should be significantly reduced without affecting the medical ...
Ramacos Fardela +4 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
, 1997 Have you ever suffered the excrutiating pain and discomfort of a severe sunburn followed by the unsightly peeling of the skin? Have you ever wondered why you may receive a sunburn even on a partially cloudy day?
Kimlin, Michael G., Parisi, Alfio
core
Invite your representative to work. Change the world. Here's how. [PDF]
, 2018 Today's political climate can seem hostile to science. Alternative facts, climate change denial, and relabeling of actual news as fake news are discouraging phenomena for sure.
Montell, Denise J
core +2 more sources
Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome
Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja +8 more
wiley +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
A nomogram to determine required seed air kerma strength in planar 131 Cesium permanent seed implant brachytherapy [PDF]
, 2019 Purpose: Intraoperatively implanted Cesium-131 ( 131 Cs) permanent seed brachytherapy is used to deliver highly localized re-irradiation in recurrent head and neck cancers.
Bar-Ad, Voichita +4 more
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source