Results 41 to 50 of about 790,793 (333)

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Desenvolvimento de software de análise gráfica para planos de radioproteção

open access: yesRevista Brasileira de Ensino de Física
Neste trabalho desenvolvemos um software que calcula os valores das doses externas numa instalação radioativa, e os apresenta graficamente em curvas de nível de doses (isodoses), utilizando o método geométrico. Ele foi criado para auxiliar as aulas sobre
Ronaldo Celso Viscovini   +2 more
doaj   +1 more source

Studies of discrete symmetries in decays of positronium atoms [PDF]

open access: yes, 2018
A positronium - a bound state of electron and positron - is an eigenstate of parity and charge conjugation operators which decays into photons. It is a unique laboratory to study discrete symmetries whose precision is limited, in principle, by the ...
Curceanu, Catalina   +31 more
core   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Evaluation of Single-Photon Emission Computed Tomography Myocardial Perfusion Detection Capability through Physical Descriptors

open access: yesApplied Sciences
A comprehensive validation of data acquired by different myocardial perfusion imaging (MPI) systems was performed to evaluate contrast, self-attenuation properties, and perfusion detection capability.
Dea Dundara Debeljuh   +4 more
doaj   +1 more source

Re-engineering a nanodosimetry Monte Carlo code into Geant4: software design and first results

open access: yes, 2009
A set of physics models for nanodosimetry simulation is being re-engineered for use in Geant4-based simulations. This extension of Geant4 capabilities is part of a larger scale R&D project for multi-scale simulation involving adaptable, co-working ...
Gargioni, E., Grichine, V., Pia, M. G.
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Fear psychosis for the medical physicists' profession in the worldwide COVID-19 crisis

open access: yesCurrent Medicine Research and Practice, 2021
Background: The coronavirus infectious disease 2019 (COVID-19) has spread over 213 countries around the world and two international conveyances. This has become a cause of public health emergencies as well as a crisis internationally.
Mahasin Gazi, Biplab Sarkar
doaj   +1 more source

Deterministic Partial Differential Equation Model for Dose Calculation in Electron Radiotherapy

open access: yes, 2009
Treatment with high energy ionizing radiation is one of the main methods in modern cancer therapy that is in clinical use. During the last decades, two main approaches to dose calculation were used, Monte Carlo simulations and semi-empirical models based
B Dubroca   +19 more
core   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

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